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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Interleukin-18 receptor accessory protein
Summary
- UniProt ID
- O95256
- Gene Symbol
-
- IL18RAP
- IL1R7
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O95256
- PubChem
- O95256
- The Human Metabolome Database
- HMDBP12409
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Hydrolase
- Immunoglobulin domain
- Inflammatory response
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| interleukin-18 receptor complex |
| GO Term |
|---|
| NAD+ nucleotidase, cyclic ADP-ribose generating |
| NAD+ nucleosidase activity |
| coreceptor activity |
| interleukin-18 receptor activity |
Sequence
MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 21 | N-linked (GlcNAc...) asparagine |
|
||
| 119 | N-linked (GlcNAc...) asparagine |
|
||
| 152 | N-linked (GlcNAc...) asparagine |
|
||
| 345 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-18 signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110748 | obsolete type 1 diabetes mellitus 9 | |
| DOID:0110749 | type 1 diabetes mellitus 10 | |
| DOID:0110750 | type 1 diabetes mellitus 11 | |
| DOID:0110751 | type 1 diabetes mellitus 12 | |
| DOID:0110752 | type 1 diabetes mellitus 13 | |
| DOID:0110753 | type 1 diabetes mellitus 15 | |
| DOID:0110754 | type 1 diabetes mellitus 17 | |
| DOID:0110755 | type 1 diabetes mellitus 18 | |
| DOID:0110756 | type 1 diabetes mellitus 19 | |
| DOID:0110757 | type 1 diabetes mellitus 20 |
