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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
GDH/6PGL endoplasmic bifunctional protein
Summary
- UniProt ID
- O95479
- Gene Symbol
-
- H6PD
- GDH
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- O95479
- PubChem
- O95479
- The Human Metabolome Database
- HMDBP00329
- The O-GlcNAc Database
- O95479
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Disease variant
- Endoplasmic reticulum
- Glucose metabolism
- Glycoprotein
- Hydrolase
- Multifunctional enzyme
- NAD
- NADP
- Oxidoreductase
- Pyrrolidone carboxylic acid
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum |
| endoplasmic reticulum lumen |
Sequence
MWNMLIVAMCLALLGCLQAQELQGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGRGHSFSFHGAALTAPKQGQELMAKALESLSCPKDMAPSHCAEHKDQFLQLSQYRQLKTAEDYQALNKDIEAQLQHAGLREAGRIFYFSVPPFAYEDIARNINSSCRPGPGAWLRVVLEKPFGHDHFSAQQLATELGTFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIIMKETVDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPHNVSSAEAVLRHKLQVFQALRGLQRGSAVVGQYQSYSEQVRRELQKPDSFHSLTPTFAAVLVHIDNLRWEGVPFILMSGKALDERVGYARILFKNQACCVQSEKHWAAAQSQCLPRQLVFHIGHGDLGSPAVLVSRNLFRPSLPSSWKEMEGPPGLRLFGSPLSDYYAYSPVRERDAHSVLLSHIFHGRKNFFITTENLLASWNFWTPLLESLAHKAPRLYPGGAENGRLLDFEFSSGRLFFSQQQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAWSEELISKLANDIEATAVRAVRRFGQFHLALSGGSSPVALFQQLATAHYGFPWAHTHLWLVDERCVPLSDPESNFQGLQAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSSFDLVLLGMGADGHTASLFPQSPTGLDGEQLVVLTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKREITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 157 | N-linked (GlcNAc...) asparagine | |||
| 282 | N-linked (GlcNAc...) asparagine | |||
| 683 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G80920RR
G39188ZX
G35029YA
G02815KT
G57317CE
G60145BJ
G92050GC
G14669DU
G28681TP
G36442WJ
G15664MX
G46691LC
G49018RC
G72747WU
G70619PT
G02886BB
G90659AW
G62765YT
G05049YU
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14221 | abdominal obesity-metabolic syndrome 1 | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:1936 | atherosclerosis | |
| DOID:2018 | hyperinsulinism | |
| DOID:2348 | arteriosclerotic cardiovascular disease | |
| DOID:2349 | arteriosclerosis | |
| DOID:2377 | multiple sclerosis | |
| DOID:2977 | primary hyperoxaluria |
