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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
L-lactate dehydrogenase A chain
Summary
- UniProt ID
- P00338
- Gene Symbol
-
- LDHA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Glycogen storage disease
- Isopeptide bond
- NAD
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| substantia nigra development |
| pyruvate metabolic process |
| glycolytic process |
| lactate metabolic process |
| GO Term |
|---|
| nucleus |
| membrane |
| extracellular exosome |
| mitochondrion |
| cytosol |
| oxidoreductase complex |
| GO Term |
|---|
| cadherin binding |
| identical protein binding |
| L-lactate dehydrogenase activity |
Sequence
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
Glycosylation Sites
G49108TO
G57776ZS
G43223CG
G92406TI
G41247ZX
G84225JN
G70994MS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Pyruvate metabolism | Homo sapiens |
| Regulation of pyruvate metabolism | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110045 | Alzheimer's disease 12 | |
| DOID:0110046 | Alzheimer's disease 13 | |
| DOID:0110047 | Alzheimer's disease 14 | |
| DOID:0110048 | Alzheimer's disease 15 | |
| DOID:0110423 | dilated cardiomyopathy 1C | |
| DOID:0110424 | dilated cardiomyopathy 1CC | |
| DOID:0110426 | dilated cardiomyopathy 1D | |
| DOID:0110427 | dilated cardiomyopathy 1V | |
| DOID:0110428 | dilated cardiomyopathy 1AA | |
| DOID:0110429 | dilated cardiomyopathy 1H |
