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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Prothrombin
Summary
- UniProt ID
- P00734
- Gene Symbol
-
- F2
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011275
- GlyConnect
- GlyGen
- P00734
- PubChem
- P00734
- The Human Metabolome Database
- HMDBP13521
- RaftProt
- P00734
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Calcium
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Gamma-carboxyglutamic acid
- Glycoprotein
- Kringle
- Pharmaceutical
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Thrombophilia
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of protein localization to nucleus |
| positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway |
| ligand-gated ion channel signaling pathway |
Sequence
MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 317 |
|
|||
| 416 | N-linked (GlcNAc...) (complex) asparagine |
|
||
|
|
G43417UB
G70232NH
G57888GL
G70888PK
G06247RL
G11629QQ
G57776ZS
G99668VU
G86880BF
G27947YN
G90093AU
G24954UD
G04854VP
G94470IW
G40834TG
G22310AV
G45395BF
G70375MX
G66163OV
G02030ZB
G26330YA
G10846ZT
G40574BA
G05933EN
G08918WF
G75983OB
G00912UN
G42358LZ
G48414YA
G84467IZ
G78790NZ
G27126ED
G27058EU
G84452RH
G46902YN
G72747WU
G60923RB
G06356OH
G37868ZX
G59626AS
G75850OP
G91365ZQ
G72398FA
G45504EY
G10486CT
G22140GZ
G50045TK
G85269DF
G95865ZB
G57776ZU
G57317CE
G28681TP
G72197KC
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of IGF Activity by IGFBP | Homo sapiens |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Homo sapiens |
| Thrombin signalling through proteinase activated receptors (PARs) | Homo sapiens |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | Homo sapiens |
