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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement C1r subcomponent
Summary
- UniProt ID
- P00736
- Gene Symbol
-
- C1R
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011276
- GlyConnect
- GlyGen
- P00736
- PubChem
- P00736
- The Human Metabolome Database
- HMDBP07480
Annotation
- Keyword
-
- 3D-structure
- Complement pathway
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Ehlers-Danlos syndrome
- Glycoprotein
- Hydroxylation
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Gene Ontology (GO)
| GO Term |
|---|
| immune response |
| innate immune response |
| complement activation, classical pathway |
| zymogen activation |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| extracellular exosome |
| blood microparticle |
| GO Term |
|---|
| serine-type endopeptidase activity |
| calcium ion binding |
| molecular sequestering activity |
| serine-type peptidase activity |
| identical protein binding |
Sequence
MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEEED
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 125 | N-linked (GlcNAc...) asparagine | |||
| 221 | N-linked (GlcNAc...) asparagine | |||
| 514 | N-linked (GlcNAc...) asparagine | |||
| 581 |
|
|
G39595FH
G64394MX
G15169WU
G11629QQ
G81263BG
G22310AV
G59536GA
G02030ZB
G08918WF
G00912UN
G48414YA
G84452RH
G92050GC
G92275SC
G93656SY
G34617SM
G41882MT
G27947YN
G98611JV
G47748JZ
G78790NZ
G27058EU
G59626AS
G80920RR
G45504EY
G37399XV
G62765YT
G10486CT
G95865ZB
G31852PQ
G72787SB
G41247ZX
G57776ZU
G57317CE
G70232NH
G06247RL
G57776ZS
G77669RF
G90382BL
G63980BQ
G04854VP
G94470IW
G40834TG
G45395BF
G59324HL
G20706XG
G40926MX
G43223CG
G40574BA
G42358LZ
G61256FT
G27126ED
G04657PL
G10488MI
G60033FS
G41071NU
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Classical antibody-mediated complement activation | Homo sapiens |
| Initial triggering of complement | Homo sapiens |
| Regulation of Complement cascade | Homo sapiens |
