Regulation of Complement cascade

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
C3AR1C3AR1:C3aC3aC5AR1C5AR1:C5aC5aC3bCFH:C3bCFHCell surface:C3bCell surface:FH,FHR3:C3bCFH, CFHR3Cell surface:CFH, CFHR3:C3bBbCFB(260-764)CFICFICFICFI:CFH:C3bC3iC3bCFI:CFH,FHR3:C3bCFI:CFH,FHR3:iC3bCR1CR1:C3bBb, C4bC2a complexesC4bC2a, C3bBbCR2CR2:C3d,C3dg,iC3bC3d, C3dg, iC3bCD46:Cell surface:C3bCD46CD46, CR1:C4b:C3b complexesCFI:CD46, CR1:C4b, C3b complexesCD55:C3 convertase complexesDAFC4bC4-binding protein:C4bC4b-binding proteinC4b-binding protein:Factor IC4dC4cC4 binding protein:C4bC2aC2aC5b:C6:C7:C8CD59:C5b-C9C9CD59VTNVTN:C5b:C6:C7C5b:C6:C7C1InhAntigen:IgG:C1Q:2xActivated C1R:2xActivated C1SAntigen:IgG:C1 with activated C1R, C1SAntigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1C1QAntigen:IgGActivated C1S:SERPING1Activated C1R:SERPING1C5C5bTC5aTC5AR2C5AR2:C5AR2 ligandsC5AR2 ligandsC3 convertasesCell surface:C4bProperdin oligomerCell surface:C4b:C2aiC3Host cell surfaceCFH:Host cell surfaceCell surface:C3b:BbCell surface:C3b:CFHR dimersCFHR dimersCR1:iC3bC3C3cCR1:C3bCR1:C4bCR2:C3d,C3dg,iC3b:CD19:CD81CD19:CD81CD46:Cell surface:C4bCD46, CR1C4d, iC3bC4c, C3fCD55:C3bCD55:C4bC4 binding protein:protein Sprotein SVTN:C5b:C6:C7:C8:C9C8C4b with hydrolysed thioesterH2OCLUCLU:C5b:C6:C7, C8, C9C5b:C6:C7, C8, C9C3a, C5aC3a-desArg, C5a-desArg
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 2 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001413 P0C0L5 Complement C4-B view
GL_002853 P04004 Vitronectin view
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International Collaboration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025