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Alpha-1-antitrypsin

Summary

UniProt ID

P01009

Gene Symbol

SERPINA1
AAT
PI

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011286

GlyConnect

GlyGen

P01009

PubChem

P01009

The O-GlcNAc Database

P01009

RaftProt

P01009

O-GlcNAcAtlas

P01009

Annotation

Keyword

3D-structure
Acute phase
Alternative splicing
Blood coagulation
Direct protein sequencing
Endoplasmic reticulum
Extracellular matrix
Glycoprotein
Phosphoprotein
Reference proteome
Serine protease inhibitor
Signal

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
blood coagulation
acute-phase response

Displaying entries **1 - 10** of 12 in total

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GO Term
extracellular region
extracellular space
Golgi apparatus
intracellular membrane-bounded organelle
collagen-containing extracellular matrix
extracellular exosome
platelet alpha granule lumen
endoplasmic reticulum
endoplasmic reticulum lumen
COPII-coated ER to Golgi transport vesicle

Displaying **all 3** entries
GO Term
protease binding
identical protein binding
serine-type endopeptidase inhibitor activity

Annotation information from UniProt.

Sequence

MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
35			G43417UB G29068FM	GlyGen
70	N-linked (GlcNAc...) (complex) asparagine	12754519 14760718 15084671 16263699 16335952 16622833 19159218 19838169 22171320	G76868JS G15127JD G41044JW G56518TU G63136LV G30740WO G78649WQ G15169WU G70232NH G55132BD G37818NZ G69521XL G70888PK G06247RL G92821YI G49589RB G12261QD G35541EV G75568BH G80075MS G57776ZS G75418YA G99668VU G77669RF G86880BF G27947YN G28622IK G90382BL G85282JO G40206WX G20528HD G37692EO G33416PL G63980BQ G04854VP G94470IW G87123QX G79666IR G92135MA G98611JV G43734MM G34989PA G40834TG G43669FQ G22310AV G45395BF G59324HL G07246CJ G85554PZ G20706XG G10819WX G40926MX G56307ZW G14972EH G43223CG G49642SA G58954YZ G37412TK G31986NC G26330YA G10846ZT G15038BD G40574BA G78787DI G08918WF G00912UN G48414YA G84467IZ G58087IP G27915IV G87389XI G23505EP G92551JA G61256FT G44211QA G34029GR G04657PL G27058EU G84452RH G51653BI G85582CB G43769HG G37509XX G70223PD G10488MI G60033FS G41071NU G86182NS G35253PZ G72747WU G70619PT G06356OH G59626AS G08290VR G25079LO G63041LO G01485JJ G73968GN G29879MS G02886BB G23863VK G31118FR G78059CC G83555HU G10486CT G22140GZ G36191CD G50045TK G90734RJ G95865ZB G75798PH G81295CK G11314AS G22572EH G92275SC G37995HC G54010QB G72197KC G84225JN G89045VA G98129XB	GlycoProtDB UniProt GlyGen GlyConnect
107	N-linked (GlcNAc...) (complex) asparagine	16335952 16622833 19139490 19159218 19838169	G69834CE G95678HJ G11115RO G12793SR G12341GU G15169WU G94917XT G77338BR G92081HT G55216FT G06247RL G47518TP G92821YI G11629QQ G85144OK G27947YN G52527GH G49739MP G43669FQ G07799LX G22310AV G88374WZ G66933CM G40926MX G59536GA G70087PV G37412TK G15038BD G82830MN G05933EN G47737VJ G00912UN G48414YA G84467IZ G44211QA G08293MJ G09528DL G20425TQ G36131WL G60033FS G46902YN G06356OH G59626AS G78059CC G83555HU G10486CT G22140GZ G36191CD G50045TK	GlycoProtDB UniProt GlyGen GlyConnect
109			G43417UB	GlyGen
137			G49108TO	GlyGen The O-GlcNAc Database
138			G49108TO	GlyGen The O-GlcNAc Database
168			G43417UB	GlyGen
271	N-linked (GlcNAc...) (complex) asparagine	12754519 14760718 15084671 16335952 16622833 19139490 19159218 19838169 22171320	G75006KF G01521EA G08609CW G63040RU G56770VP G81637OR G95046LV G56518TU G01160VV G25541YH G05962QB G30740WO G15169WU G70232NH G94917XT G70888PK G92081HT G03644CB G33791AF G06247RL G47518TP G92821YI G49589RB G75568BH G80075MS G11629QQ G57776ZS G29545VG G91116OD G68490OW G99668VU G77669RF G86795LJ G86880BF G27947YN G52527GH G28622IK G90382BL G30970QQ G30248BL G40206WX G37692EO G78502KD G33416PL G63980BQ G04854VP G76329HL G94470IW G87123QX G79666IR G81263BG G92135MA G26403SG G98611JV G75607BQ G34989PA G47748JZ G06330RB G40834TG G86500WE G43669FQ G07799LX G51413EV G08146BT G22310AV G45395BF G88374WZ G59324HL G07246CJ G70375MX G85554PZ G02628JF G20706XG G10819WX G40926MX G59536GA G77459ND G56307ZW G14972EH G02030ZB G43223CG G64275UO G58954YZ G95977AE G37412TK G31986NC G86226EA G26330YA G10846ZT G60177UT G15038BD G40574BA G82830MN G78787DI G00273SJ G05933EN G08918WF G71146HJ G75983OB G00912UN G42358LZ G48414YA G84467IZ G49906RN G78790NZ G58087IP G89098OM G11911BT G87389XI G23505EP G92551JA G61256FT G70441OD G72797UR G70822IO G87661QW G83646BJ G36442WJ G63381RX G76295SF G15664MX G66621EA G46691LC G25418HZ G27126ED G34029GR G04657PL G25451PN G08293MJ G27058EU G45495MK G84452RH G46524LG G51653BI G43769HG G37509XX G51640FO G70223PD G41071NU G07755XJ G86182NS G49018RC G35253PZ G46902YN G72747WU G42962KI G44215PV G60923RB G70619PT G06356OH G37868ZX G59626AS G72398FA G84862VB G08290VR G14994KB G92406TI G46503DX G41840AI G01650EU G25079LO G80920RR G01485JJ G73968GN G65184UU G42124LM G02886BB G78059CC G83555HU G90659AW G77547TA G31916IQ G45504EY G29299MO G37399XV G82463GQ G83624CJ G83633GK G62765YT G47644PP G72790NZ G10486CT G22140GZ G36191CD G50045TK G05049YU G28541PG G85269DF G72291OX G95865ZB G31852PQ G96993FE G72787SB G22572EH G41247ZX G57776ZU G02815KT G57317CE G14669DU G28681TP G37995HC G54010QB G72197KC G84225JN G89045VA G98129XB	GlycoProtDB UniProt GlyGen GlyConnect
273			G12728EY G11911BT	GlyGen GlyConnect
414			G64394MX G93656SY G57888GL G37881RL G59536GA G84452RH	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
COPII-mediated vesicle transport	Homo sapiens
Cargo concentration in the ER	Homo sapiens
Neutrophil degranulation	Homo sapiens
Platelet degranulation	Homo sapiens
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens

Human Protein Atlas

ENSG00000197249

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements