GlyCosmos Portal

Submissions

Pro-epidermal growth factor

Summary

UniProt ID

P01133

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlyConnect

GlyGen

P01133

PubChem

P01133

The Human Metabolome Database

HMDBP02438

The O-GlcNAc Database

P01133

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disease variant
Disulfide bond
EGF-like domain
Glycoprotein
Growth factor
Primary hypomagnesemia
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 35 in total

1

2

3

4

Next ›

Last »
GO Term
angiogenesis
positive regulation of endothelial cell proliferation
positive regulation of cell population proliferation
positive regulation of gene expression
positive regulation of cell migration
positive regulation of phosphorylation
branching morphogenesis of an epithelial tube
positive regulation of epithelial tube formation
positive regulation of hyaluronan biosynthetic process
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

Displaying **all 7** entries
GO Term
extracellular region
extracellular space
lysosomal membrane
plasma membrane
extracellular exosome
clathrin-coated endocytic vesicle membrane
platelet alpha granule lumen

Displaying **all 8** entries
GO Term
Wnt-protein binding
Wnt receptor activity
receptor ligand activity
guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
growth factor activity
calcium ion binding
transmembrane receptor protein tyrosine kinase activator activity

Annotation information from UniProt.

Sequence

MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPHQMELTQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 15** of 15 in total

« First

‹ Prev

1

2
Position	Description	GlyTouCan ID	Source
815	N-linked (GlcNAc...) asparagine		UniProt GlyGen
926	N-linked (GlcNAc...) asparagine		UniProt GlyGen
954		G53434XO G43417UB	GlyGen
955		G53434XO G43417UB	GlyGen
1125		G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **21 - 30** of 33 in total

« First

‹ Prev

1

2

3

4

Next ›

Last »
Pathway Name	Organism
PI3K/AKT Signaling	Homo sapiens
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Homo sapiens
PLCG1 events in ERBB2 signaling	Homo sapiens
Platelet degranulation	Homo sapiens
RAF/MAP kinase cascade	Homo sapiens
SHC1 events in EGFR signaling	Homo sapiens
SHC1 events in ERBB2 signaling	Homo sapiens
Signaling by EGFR	Homo sapiens
Signaling by ERBB2	Homo sapiens
Signaling by ERBB2 ECD mutants	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements