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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Apolipoprotein A-I
Summary
- UniProt ID
- P02647
- Gene Symbol
-
- APOA1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P02647
- PubChem
- P02647
- The Human Metabolome Database
- HMDBP01620
- RaftProt
- P02647
Annotation
- Keyword
-
- 3D-structure
- Amyloid
- Amyloidosis
- Atherosclerosis
- Cholesterol metabolism
- Direct protein sequencing
- Disease variant
- Glycation
- HDL
- Lipid transport
- Neuropathy
- Oxidation
- Palmitate
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| plasma membrane |
| endocytic vesicle |
| cytoplasmic vesicle |
| collagen-containing extracellular matrix |
| extracellular exosome |
| endocytic vesicle lumen |
| extracellular vesicle |
| secretory granule lumen |
| GO Term |
|---|
| phospholipid binding |
| high-density lipoprotein particle binding |
| apolipoprotein receptor binding |
| apolipoprotein A-I receptor binding |
| high-density lipoprotein particle receptor binding |
Sequence
MKAAVLTLAVLFLTGSQARHFWQQDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQ
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ABC transporters in lipid homeostasis | Homo sapiens |
| Amyloid fiber formation | Homo sapiens |
| Chylomicron assembly | Homo sapiens |
| Chylomicron remodeling | Homo sapiens |
| Defective ABCA1 causes TGD | Homo sapiens |
| HDL assembly | Homo sapiens |
| HDL clearance | Homo sapiens |
| HDL remodeling | Homo sapiens |
| Heme signaling | Homo sapiens |
| PPARA activates gene expression | Homo sapiens |
