Amyloid fiber formation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PolyUbSynphilin-1SNCAIPSIAH1,SIAH2:UBE2L6:Ubiquitin:SNCASIAH1:UBE2L6:Ub-SNCAFAMUSP9X:Ub-SNCAUb-SNCAUSPX9:SNCASNCA7K-BACE17K-BACE1BACE1_HUMANCH3COO-H2OBACE1_HUMANBACE1_HUMANBACE1:GGA1,2,3GGA1,2,3Beta-amyloidBeta-amyloidHSPG2Amyloid fibrilsSerum amyloid P-component homopentamerAPOE-4Amyloid fibril main peptide chainsGAGADAM10:Zn2+ADAM10:Zn2+:TSPANsTSPANsAPPAPPAPPSIAH1, SIAH2:SNCAIPSIAH1, SIAH2PARK2:SNCAIPPRKNSynphilin-1K63polyUbSIAH1,SIAH2:UBE2L6:UbiquitinSIAH1UBCH8UbSNCAIP:SNCAsSNCAsCa2+APCSAc-CoACoA-SHBACE1BACE1_HUMANBACE1APPC99APPC99C99C99C99SORL1SORL1:APP(18-770)SORL1:APP(18-770)Amyloid fibril monomersSerum amyloid P decamerSerum amyloid P-component pentamer:Double-stranded DNADouble-stranded DNA and chromatinCa2+CALB1:4xCa2+CALB1ADAM10:Zn2+:TSPANs
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 58 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
A1E959 Odontogenic ameloblast-associated protein
  • APIN
  • ODAM
view
O14672 Disintegrin and metalloproteinase domain-containing protein 10
  • ADAM10
  • KUZ
  • MADM
view
O60814 Histone H2B type 1-K
  • H2BC12
  • H2BFT
  • HIRIP1
  • HIST1H2BK
view
O95858 Tetraspanin-15
  • NET7
  • TM4SF15
  • TSPAN15
view
P01160 Natriuretic peptides A
  • ANP
  • NPPA
  • PND
view
P01236 Prolactin
  • PRL
view
P01258 Calcitonin
  • CALC1
  • CALCA
view
P02647 Apolipoprotein A-I
  • APOA1
view
P02649 Apolipoprotein E
  • APOE
view
P02671 Fibrinogen alpha chain
  • FGA
view
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001101 P02743 Serum amyloid P-component view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025