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Complement C1q subcomponent subunit A
Summary
- UniProt ID
- P02745
- Gene Symbol
-
- C1QA
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011308
- GlyConnect
- GlyGen
- P02745
- PubChem
- P02745
- The Human Metabolome Database
- HMDBP07477
Annotation
- Keyword
-
- 3D-structure
- Collagen
- Complement pathway
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Host-virus interaction
- Hydroxylation
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| collagen trimer |
| synapse |
| collagen-containing extracellular matrix |
| postsynapse |
| complement component C1 complex |
| complement component C1q complex |
| GO Term |
|---|
| amyloid-beta binding |
Sequence
MEGPRGWLVLCVLAISLASMVTEDLCRAPDGKKGEAGRPGRRGRPGLKGEQGEPGAPGIRTGIQGLKGDQGEPGPSGNPGKVGYPGPSGPLGARGIPGIKGTKGSPGNIKDQPRPAFSAIRRNPPMGGNVVIFDTVITNQEEPYQNHSGRFVCTVPGYYYFTFQVLSQWEICLSIVSSSRGQVRRSLGFCDTTNKGLFQVVSGGMVLQLQQGDQVWVEKDPKKGHIYQGSEADSVFSGFLIFPSA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 33 | O-linked (Gal...) hydroxylysine |
|
||
| 48 | O-linked (Gal...) hydroxylysine |
|
||
| 67 | O-linked (Gal...) hydroxylysine |
|
||
| 100 | O-linked (Gal...) hydroxylysine |
|
||
| 146 | N-linked (GlcNAc...) asparagine |
|
G67164EE
G80075MS
G77669RF
G04854VP
G94470IW
G87123QX
G79666IR
G81263BG
G86752LQ
G40834TG
G43669FQ
G22310AV
G45395BF
G88374WZ
G59324HL
G20706XG
G10819WX
G40926MX
G10846ZT
G40574BA
G00273SJ
G08918WF
G00912UN
G48414YA
G92551JA
G61256FT
G15664MX
G46691LC
G27126ED
G04657PL
G08293MJ
G27058EU
G84452RH
G24528MX
G83460ZZ
G72747WU
G70619PT
G06356OH
G59626AS
G25079LO
G80920RR
G23863VK
G83555HU
G90659AW
G62765YT
G10486CT
G28541PG
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Classical antibody-mediated complement activation | Homo sapiens |
| Initial triggering of complement | Homo sapiens |
| Regulation of Complement cascade | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
