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MIRAGE
Complement component C9

Summary
UniProt ID
P02748
Gene Symbol
  • C9
Gene ID
735
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011309
GlyConnect
GlyGen
P02748
PubChem
P02748
RaftProt
P02748
Re-Glyco
P02748
Annotation
Keyword
  • 3D-structure
  • Age-related macular degeneration
  • Complement alternate pathway
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Membrane attack complex
  • Phosphoprotein
  • Reference proteome
  • Secreted
  • Signal
  • Target cell membrane
  • Transmembrane beta strand
Gene Ontology (GO)
Displaying all 7 entries
GO Term
blood microparticle
membrane attack complex
other organism cell membrane
extracellular region
extracellular space
plasma membrane
extracellular exosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MSACRSFAVAICILEISILTAQYTTSYDPELTESSGSASHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRCTDAVGDRRQCVPTEPCEDAEDDCGNDFQCSTGRCIKMRLRCNGDNDCGDFSDEDDCESEPRPPCRDRVVEESELARTAGYGINILGMDPLSTPFDNEFYNGLCNRDRDGNTLTYYRRPWNVASLIYETKGEKNFRTEHYEEQIEAFKSIIQEKTSNFNAAISLKFTPTETNKAEQCCEETASSISLHGKGSFRFSYSKNETYQLFLSYSSKKEKMFLHVKGEIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEYFAFLETYGTHYSSSGSLGGLYELIYVLDKASMKRKGVELKDIKRCLGYHLDVSLAFSEISVGAEFNKDDCVKRGEGRAVNITSENLIDDVVSLIRGGTRKYAFELKEKLLRGTVIDVTDFVNWASSINDAPVLISQKLSPIYNLVPVKMKNAHLKKQNLERAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFEGIACEISKQKISEGLPALEFPNEK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 10 entries
Position Description PubMed ID GlyTouCan ID Source
24
26
32
48 C-linked (Man) tryptophan
51 C-linked (Man) tryptophan; partial
123
258
277 N-linked (GlcNAc...) asparagine
415 N-linked (GlcNAc...) (complex) asparagine
518
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Regulation of Complement cascade Homo sapiens
Terminal pathway of complement Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:0060303 complement component 9 deficiency
DOID:0110027 age related macular degeneration 15
DOID:2559 opiate dependence
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025