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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Repository for lectin-assisted multimodality data
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Guidelines
MIRAGE
Granulocyte-macrophage colony-stimulating factor
Summary
- UniProt ID
- P04141
- Gene Symbol
-
- CSF2
- GMCSF
- Gene ID
- 1437
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytokine
- Disulfide bond
- Glycoprotein
- Growth factor
- Pharmaceutical
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| granulocyte macrophage colony-stimulating factor receptor binding |
| cytokine activity |
| growth factor activity |
Sequence
MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 5 |
|
|
||
| 22 | O-linked (GalNAc...) serine | |||
| 24 | O-linked (GalNAc...) serine |
|
||
| 26 | O-linked (GalNAc...) serine |
|
||
| 27 | O-linked (GalNAc...) threonine; partial |
|
||
| 44 |
|
|
||
| 54 |
|
|
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin receptor SHC signaling | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050458 | juvenile myelomonocytic leukemia | |
| DOID:12120 | pulmonary alveolar proteinosis | |
| DOID:1227 | neutropenia | |
| DOID:9119 | acute myeloid leukemia | |
| DOID:9146 | visceral leishmaniasis |
