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Standards Ontologies Notations
Phosphatidylcholine-sterol acyltransferase

Summary
UniProt ID
P04180
Gene Symbol
  • LCAT
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011357
GlyConnect
GlyGen
P04180
PubChem
P04180
SwissLipids
The Human Metabolome Database
HMDBP00069
Annotation
Keyword
  • 3D-structure
  • Acyltransferase
  • Cholesterol metabolism
  • Corneal dystrophy
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Hydrolase
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLGAYRQGPPASPTASPEPPPPE
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
44 N-linked (GlcNAc...) (complex) asparagine
108 N-linked (GlcNAc...) (complex) asparagine
296 N-linked (GlcNAc...) (complex) asparagine
408 N-linked (GlcNAc...) (complex) asparagine
424
431 O-linked (GalNAc...) threonine
433 O-linked (GalNAc...) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
HDL remodeling Homo sapiens
Disease
Displaying entries 121 - 130 of 150 in total
DO ID Disease Name Source
DOID:2349 arteriosclerosis
DOID:2355 anemia
DOID:2361 macrocytic anemia
DOID:2394 ovarian cancer
DOID:2477 motor peripheral neuropathy
DOID:2527 nephrosis
DOID:2565 macular corneal dystrophy
DOID:2566 corneal dystrophy
DOID:2590 familial nephrotic syndrome
DOID:2717 Bloom syndrome
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024