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Standards Ontologies Notations
Phosphatidylcholine-sterol acyltransferase

Summary
UniProt ID
P04180
Gene Symbol
  • LCAT
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011357
GlyConnect
GlyGen
P04180
PubChem
P04180
SwissLipids
The Human Metabolome Database
HMDBP00069
Annotation
Keyword
  • 3D-structure
  • Acyltransferase
  • Cholesterol metabolism
  • Corneal dystrophy
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Hydrolase
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying entries 11 - 12 of 12 in total
GO Term
lipid metabolic process
lipoprotein biosynthetic process
Annotation information from UniProt.
Sequence
MGPPGSPWQWVTLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQPQAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWPEDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTYIYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHINAILLGAYRQGPPASPTASPEPPPPE
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
44 N-linked (GlcNAc...) (complex) asparagine
108 N-linked (GlcNAc...) (complex) asparagine
296 N-linked (GlcNAc...) (complex) asparagine
408 N-linked (GlcNAc...) (complex) asparagine
424
431 O-linked (GalNAc...) threonine
433 O-linked (GalNAc...) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
HDL remodeling Homo sapiens
Disease
Displaying entries 31 - 40 of 150 in total
DO ID Disease Name Source
DOID:0110156 Charcot-Marie-Tooth disease type 2B1
DOID:0110157 Charcot-Marie-Tooth disease type 2J
DOID:0110158 Charcot-Marie-Tooth disease type 2I
DOID:0110159 Charcot-Marie-Tooth disease type 2B
DOID:0110160 Charcot-Marie-Tooth disease axonal type 2T
DOID:0110161 Charcot-Marie-Tooth disease type 2R
DOID:0110163 Charcot-Marie-Tooth disease axonal type 2F
DOID:0110164 Charcot-Marie-Tooth disease type 2D
DOID:0110165 Charcot-Marie-Tooth disease type 2E
DOID:0110166 Charcot-Marie-Tooth disease axonal type 2H
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024