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Histidine-rich glycoprotein

Summary

UniProt ID

P04196

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011358

GlyConnect

GlyGen

P04196

PubChem

P04196

The Human Metabolome Database

HMDBP02730

Annotation

Keyword

Angiogenesis
Chemotaxis
Cleavage on pair of basic residues
Copper
Direct protein sequencing
Disease variant
Disulfide bond
Fibrinolysis
Glycoprotein
Heparin-binding
Metal-binding
Reference proteome
Repeat
Secreted
Signal
Thrombophilia
Zinc

Gene Ontology (GO)

Displaying entries **11 - 20** of 27 in total

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GO Term
chemotaxis
negative regulation of cell adhesion
negative regulation of cell population proliferation
regulation of gene expression
regulation of platelet activation
negative regulation of angiogenesis
platelet activation
regulation of blood coagulation
negative regulation of cell growth
fibrinolysis

Displaying **all 7** entries
GO Term
cell surface
extracellular region
plasma membrane
extracellular exosome
blood microparticle
collagen-containing extracellular matrix
platelet alpha granule lumen

Displaying **all 9** entries
GO Term
serine-type endopeptidase inhibitor activity
cysteine-type endopeptidase inhibitor activity
immunoglobulin binding
heme binding
heparan sulfate proteoglycan binding
signaling receptor binding
heparin binding
zinc ion binding
metal ion binding

Annotation information from UniProt.

Sequence

MKALIAALLLITLQYSCAVSPTDCSAVEPEAEKALDLINKRRRDGYLFQLLRIADAHLDRVENTTVYYLVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHSHESQDLRVIDFNCTTSSVSSALANTKDSPVLIDFFEDTERYRKQANKALEKYKEENDDFASFRVDRIERVARVRGGEGTGYFVDFSVRNCPRHHFPRHPNVFGFCRADLFYDVEALDLESPKNLVINCEVFDPQEHENINGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSFPLPHHKHPLKPDNQPFPQSVSESCPGKFKSGFPQVSMFFTHTFPK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
63	N-linked (GlcNAc...) asparagine	16335952 19285951	G47518TP G24084IV G22310AV G45395BF G40574BA G82830MN G08918WF G47737VJ G00912UN G48414YA G06356OH	UniProt GlyGen GlyConnect
125	N-linked (GlcNAc...) asparagine	16335952 19159218	G81637OR G65414LI G50856PC G45526EA G12341GU G70232NH G44753VC G40206WX G37692EO G63980BQ G04854VP G94470IW G40834TG G45395BF G85554PZ G14972EH G43223CG G95977AE G31986NC G26330YA G10846ZT G40574BA G82830MN G00273SJ G05933EN G08918WF G75983OB G00912UN G42358LZ G48414YA G49906RN G58087IP G27915IV G89098OM G11911BT G92551JA G61256FT G83646BJ G17208MA G76295SF G15664MX G46691LC G25418HZ G27126ED G04657PL G08293MJ G27058EU G84452RH G46524LG G43769HG G37509XX G49018RC G46902YN G72747WU G70619PT G06356OH G37868ZX G59626AS G92406TI G41840AI G01650EU G23294PN G80920RR G77547TA G45504EY G65000LJ G59924QI G29299MO G37399XV G82463GQ G10486CT G50045TK G28541PG G18647XP G85269DF G72291OX G95865ZB G39446WN G22572EH G41247ZX G57776ZU G36379GD G02815KT G57317CE G28681TP G37995HC	GlycoProtDB UniProt GlyGen GlyConnect
271			G53434XO G43417UB G29068FM G57321FI	GlyGen
273			G43417UB	GlyGen
274			G29068FM	GlyGen
344	N-linked (GlcNAc...) asparagine	16335952	G71560PC G89205CJ G31665QC G55412XP G33791AF G85144OK G04854VP G94470IW G92135MA G45395BF G88374WZ G14972EH G43223CG G08918WF G47737VJ G00912UN G48414YA G92551JA G61256FT G27058EU G60923RB G06356OH G59626AS G10486CT G95865ZB	UniProt GlyGen GlyConnect
345	N-linked (GlcNAc...) asparagine		G85144OK G27947YN G88374WZ G00912UN G08293MJ G59626AS G10486CT	UniProt GlyGen