Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Amyloid-beta precursor protein
Summary
- UniProt ID
- P05067
- Gene Symbol
-
- APP
- A4
- AD1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011374
- GlyConnect
- GlyGen
- P05067
- PubChem
- P05067
- The Human Metabolome Database
- HMDBP01991
- RaftProt
- P05067
- O-GlcNAcAtlas
- P05067
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Alzheimer disease
- Amyloid
- Amyloidosis
- Apoptosis
- Cell adhesion
- Cell membrane
- Cell projection
- Coated pit
- Copper
- Cytoplasm
- Cytoplasmic vesicle
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endocytosis
- Endoplasmic reticulum
- Endosome
- Golgi apparatus
- Heparin-binding
- Iron
- Isopeptide bond
- Metal-binding
- Neurodegeneration
- Notch signaling pathway
- Nucleus
- Oxidation
- Phosphoprotein
- Proteoglycan
- Reference proteome
- Secreted
- Serine protease inhibitor
- Signal
- Sulfation
- Transmembrane helix
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| endosome |
| early endosome |
| endoplasmic reticulum |
| endoplasmic reticulum lumen |
| Golgi apparatus |
| Golgi lumen |
| Golgi-associated vesicle |
| cytosol |
| cell surface |
| apical part of cell |
| GO Term |
|---|
| signaling receptor binding |
| heparin binding |
Sequence
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 367 |
|
|||
| 370 |
|
|||
| 371 |
|
|||
| 378 |
|
|||
| 381 |
|
|||
| 542 | N-linked (GlcNAc...) asparagine | |||
| 571 | N-linked (GlcNAc...) asparagine | |||
| 586 |
|
|||
| 600 |
|
|||
| 633 | O-linked (GalNAc...) threonine; partial |
G43417UB
G57321FI
G53434XO
G45395BF
G46503DX
G25079LO
G80920RR
G62765YT
G88891KO
G72787SB
G41247ZX
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of IGF Activity by IGFBP | Homo sapiens |
| TAK1-dependent IKK and NF-kappa-B activation | Homo sapiens |
| TRAF6 mediated NF-kB activation | Homo sapiens |
| The NLRP3 inflammasome | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
