GlyCosmos Portal

Submissions

Complement factor I

Summary

UniProt ID

P05156

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011391

GlyConnect

GlyGen

P05156

PubChem

P05156

RaftProt

P05156

Annotation

Keyword

3D-structure
Age-related macular degeneration
Calcium
Cleavage on pair of basic residues
Complement pathway
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Hemolytic uremic syndrome
Host-virus interaction
Metal-binding
Reference proteome
Repeat
Secreted
Serine protease
Signal

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
complement activation, classical pathway
proteolysis
innate immune response

Displaying **all 4** entries
GO Term
extracellular exosome
extracellular region
extracellular space
membrane

Displaying **all 2** entries
GO Term
serine-type endopeptidase activity
metal ion binding

Annotation information from UniProt.

Sequence

MKLLHVFLLFLCFHLRFCKVTYTSQEDLVEKKCLAKKYTHLSCDKVFCQPWQRCIEGTCVCKLPYQCPKNGTAVCATNRRSFPTYCQQKSLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVTQEETEILTADMDAERRRIKSLLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVANYFDWISYHVGRPFISQYNV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
70	N-linked (GlcNAc...) asparagine	16335952 21768352	G32788FZ G27947YN G56784JY G22310AV G00912UN G27058EU G83460ZZ G41071NU G06356OH G59626AS G73430PD G80920RR G90659AW G62765YT G10486CT G31852PQ G41247ZX	UniProt GlyGen GlyConnect
103	N-linked (GlcNAc...) (complex) asparagine	16335952 19139490 19159218 19838169 21768352	G70232NH G06247RL G52527GH G04854VP G45395BF G26330YA G40574BA G08918WF G00912UN G48414YA G11911BT G87661QW G83646BJ G27126ED G27058EU G51653BI G83460ZZ G41071NU G86182NS G70619PT G06356OH G59626AS G46503DX G01650EU G80920RR G65184UU G42124LM G90659AW G37399XV G62765YT G72790NZ G10486CT G22140GZ G50045TK G95865ZB G31852PQ G41247ZX G02815KT G66538GV G92050GC G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
177	N-linked (GlcNAc...) asparagine	16335952 21768352	G56518TU G15169WU G70232NH G94917XT G06247RL G47518TP G11629QQ G85144OK G77669RF G27947YN G52527GH G04854VP G94470IW G43669FQ G22310AV G45395BF G88374WZ G08918WF G75983OB G00912UN G48414YA G92551JA G61256FT G15664MX G08293MJ G27058EU G45495MK G84452RH G83460ZZ G70619PT G06356OH G59626AS G80920RR G23863VK G83555HU G62765YT G10486CT G50045TK G31852PQ G41247ZX	GlycoProtDB UniProt GlyGen GlyConnect
464	N-linked (GlcNAc...) asparagine	14760718 16335952 21768352	G70232NH G06247RL G86880BF G27947YN G04854VP G94470IW G45395BF G31986NC G26330YA G10846ZT G40574BA G82830MN G08918WF G00912UN G48414YA G92551JA G27058EU G51653BI G83460ZZ G41071NU G72747WU G70619PT G06356OH G59626AS G80920RR G62765YT G10486CT G31852PQ G37995HC	GlycoProtDB UniProt GlyGen GlyConnect
494	N-linked (GlcNAc...) asparagine	21768352	G49329XU G80586MF G70232NH G70888PK G06247RL G86880BF G27947YN G22310AV G45395BF G26330YA G40574BA G08918WF G00912UN G48414YA G27126ED G27058EU G24528MX G51653BI G83460ZZ G71569SN G41071NU G86182NS G72747WU G70619PT G06356OH G59626AS G92406TI G01650EU G80920RR G63041LO G65184UU G45504EY G62765YT G10486CT G95865ZB G31852PQ G90575OW G39188ZX G41247ZX G57776ZU G02815KT G57317CE G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
536	N-linked (GlcNAc...) asparagine	16335952 21768352	G47737VJ G00912UN G48414YA G06356OH	UniProt GlyGen GlyConnect