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MIRAGE
Estrogen receptor
Summary
- UniProt ID
- P06211
- Gene Symbol
-
- Esr
- Esr1
- Estr
- Nr3a1
- Gene ID
- 24890
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Activator
- Cell membrane
- Cytoplasm
- DNA-binding
- Glycoprotein
- Golgi apparatus
- Methylation
- Nucleus
- Palmitate
- Phosphoprotein
- Receptor
- Reference proteome
- Steroid-binding
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| chromatin |
| euchromatin |
| nucleus |
| plasma membrane |
| protein-containing complex |
| Golgi apparatus |
| T-tubule |
| perinuclear region of cytoplasm |
| transcription regulator complex |
| GO Term |
|---|
| DNA binding |
| steroid binding |
| calmodulin binding |
| enzyme binding |
| protein kinase binding |
| nuclear estrogen receptor binding |
| hormone binding |
| identical protein binding |
| sequence-specific DNA binding |
| protein-containing complex binding |
Sequence
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPAVFNYPEGAAYEFNAAAAAAAAGASAPVYGQSSITYGPGSEAAAFGANSLGAFPQLNSVSPSPLMLLHPPPHVSPFLHPHGHQVPYYLENEPSAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSSEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGTSGDMRAANLWPSPLVIKHTKKNSPALSLTADQMVSALLDAEPPLIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKINDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAPASRMGVPPEEPSQSQLTTTSSTSAHSLQTYYIPPEAEGFPNTI
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ESR-mediated signaling | Rattus norvegicus |
| Estrogen-dependent gene expression | Rattus norvegicus |
| Extra-nuclear estrogen signaling | Rattus norvegicus |
| Mitochondrial unfolded protein response (UPRmt) | Rattus norvegicus |
| Nuclear Receptor transcription pathway | Rattus norvegicus |
| Nuclear signaling by ERBB4 | Rattus norvegicus |
| Ovarian tumor domain proteases | Rattus norvegicus |
| PI3K/AKT Signaling | Rattus norvegicus |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Rattus norvegicus |
| RUNX1 regulates estrogen receptor mediated transcription | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080855 | Parkinsonism | |
| DOID:10247 | pleurisy | |
| DOID:11132 | prostatic hypertrophy | |
| DOID:224 | transient cerebral ischemia | |
| DOID:5223 | infertility | |
| DOID:8283 | peritonitis | |
| DOID:8634 | prostate carcinoma in situ | |
| DOID:9970 | obesity |
