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MIRAGE
Estrogen-dependent gene expression

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ESR1 dimer:ESTGERBB4s80:ESR1:estrogenERBB4s80Pou2f1CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOSEp300ESTG:ESR1 dimer:JUN:FOSESTG:ESR1 dimer:ATF2:JUNCCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3Foxa1Yy1CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1GATA3Hdac1KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4BKDM4B-regulated genes:H3K9me3 nucleosomeKdm4bKDM4B-regulated genes:nucleosome:ESR1:ESTGQ9QWM1GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2Ncoa3GREB1 gene:nucleosome:ESR1:ESTGZfp217GREB1:ESR1:ESTG:EP300:CREBBPGreb1CREBBPESR1:ESTG:P-TEFbMYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFbMYB gene:hypophosphorylated RNA polymerase II:TFIIFTFF3 gene:FOXA1:GATA3TFF3 gene:FOXA1:GATA3:ESR1:ESTG:EP300TFF1 gene:FOXA1:GATA3ESR1:estrogen:TFF1 gene:FOXA1:GATA3ESR1 dimer:estrogenESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5Ddx5TbpTBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3TFIIACARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3CARM1PRMT1ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATshistone acetyltransferasesESR1 dimer:estrogen:TGFA gene promoterESR1 dimer:estrogen:TFGA gene:NCOA1Ncoa1ESR1:estrogen:TFGA gene:NCOA1:EP300ESR1:estrogen:ERE:NCOA3:TFGA geneESR1:estrogen:ERE:NCOA3:EP300MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTGMYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1AKDM1AMYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTGMYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG:EP300RUNX1:CBFB:ESR1:estrogenRUNX1:CBFBPtges3ESR1:ER:PGR:P4HSP90:ATP:PTGES3:FKBP52:PGR:P4HSP90:HSP90PiFkbp4ADPTle3ESR1:ESTG:PGR:P4:FOXA1:GATA3:TLE3:NRIP:EP300Nrip1MYB gene:hyperphosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFbATPCITED1:EP300:ESR1:estrogen:TGFA gene promoterCited1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
A0A8I6APA0 Nuclear receptor coactivator
  • Ncoa1
 view
P06211 Estrogen receptor
  • Esr
  • Esr1
  • Estr
  • Nr3a1
 view
P34058 Heat shock protein HSP 90-beta
  • Hsp84
  • Hsp90ab1
  • Hspc3
  • Hspcb
 view
Q00969 Cyclic AMP-dependent transcription factor ATF-2
  • Atf2
 view
Q63046 Runt-related transcription factor 1
  • Aml1
  • Cbfa2
  • Runx1
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025