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Runt-related transcription factor 1

Summary

UniProt ID

Q63046

Gene Symbol

Runx1
Aml1
Cbfa2

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q63046
PubChem: Q63046
The O-GlcNAc Database: Q63046

Annotation

Keyword

Acetylation
Activator
DNA-binding
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repressor
Transcription regulation

Gene Ontology (GO)

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GO Term
skeletal system development
ossification
in utero embryonic development
liver development
chondrocyte differentiation
myeloid progenitor cell differentiation
myeloid leukocyte differentiation
regulation of T cell anergy
central nervous system development
negative regulation of cell population proliferation

Displaying **all 4** entries
GO Term
chromatin
basement membrane
nucleus
core-binding factor complex

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GO Term
DNA binding
DNA-binding transcription factor binding
promoter-specific chromatin binding
transcription cis-regulatory region binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific double-stranded DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDGGAALASKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDARQIQPSPPWSYDQSYQYLGSITSSVHPATPISPGRASGMTSLSAELSSRLSTAPDLTAFGDPRQFPTLPSISDPRMHYPGAFTYSPPVTSGIGIGMSAMSSTSRYHTYLPPPYPGSSQAQAGPFQTGSPSYHLYYGTSAGSYQFSMVGGERSPPRILPPCTNASTGAALLNPSLPSQSDVVETEGSHSNSPTNMPPARLEEAVWRPY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Estrogen-dependent gene expression	Rattus norvegicus
Organic cation transport	Rattus norvegicus
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	Rattus norvegicus
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Rattus norvegicus
RUNX1 regulates estrogen receptor mediated transcription	Rattus norvegicus
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Rattus norvegicus
RUNX1 regulates transcription of genes involved in BCR signaling	Rattus norvegicus
RUNX1 regulates transcription of genes involved in differentiation of HSCs	Rattus norvegicus
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	Rattus norvegicus
RUNX1 regulates transcription of genes involved in interleukin signaling	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements