GlyCosmos Portal

Submissions

Alpha-galactosidase A

Summary

UniProt ID

P06280

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011404

GlyConnect

1005

GlyGen

P06280

PubChem

P06280

SwissLipids

SLP:000001380

The Human Metabolome Database

HMDBP00723

Annotation

Keyword

3D-structure
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Glycosidase
Lipid metabolism
Lysosome
Pharmaceutical
RNA editing
Reference proteome
Signal

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
oligosaccharide metabolic process
glycosylceramide catabolic process
glycosphingolipid catabolic process
negative regulation of nitric-oxide synthase activity
glycoside catabolic process
negative regulation of nitric oxide biosynthetic process

Displaying **all 7** entries
GO Term
Golgi apparatus
extracellular region
cytoplasm
lysosome
azurophil granule lumen
lysosomal lumen
extracellular exosome

Displaying **all 6** entries
GO Term
signaling receptor binding
galactoside binding
catalytic activity
hydrolase activity
alpha-galactosidase activity
protein homodimerization activity

Annotation information from UniProt.

Sequence

MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTMQMSLKDLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
139	N-linked (GlcNAc...) asparagine	15003450	G76417NN G15169WU G70232NH G06247RL G90382BL G34989PA G43669FQ G47012YE G45395BF G37412TK G75983OB G00912UN G48414YA G83460ZZ G70101JE G80920RR G12313PD G82463GQ G62765YT G62894KT G11870QZ G47644PP G72291OX G31852PQ G23719VF G41247ZX G74724QE G92275SC G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
192	N-linked (GlcNAc...) asparagine	15003450	G23294PN G01937VC G05724UK G31852PQ G39188ZX G41247ZX G06110VR G14669DU	UniProt GlyGen GlyConnect
215	N-linked (GlcNAc...) asparagine	15003450 19159218	G27058EU G29184RN G96091TT G46503DX G95995BI G62894KT G47644PP G31852PQ G90575OW G39188ZX G41247ZX G50282JC G06110VR G00406II G74724QE G92275SC	GlycoProtDB UniProt GlyGen GlyConnect