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MIRAGE
Tumor necrosis factor receptor superfamily member 16
Summary
- UniProt ID
- P07174
- Gene Symbol
-
- Ngfr
- Tnfrsf16
- Gene ID
- 24596
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Apoptosis
- Biological rhythms
- Cell membrane
- Cell projection
- Developmental protein
- Differentiation
- Disulfide bond
- Glycoprotein
- Neurogenesis
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Synapse
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| nuclear envelope |
| cytoplasm |
| mitochondrion |
| plasma membrane |
| cell-cell junction |
| neuromuscular junction |
| external side of plasma membrane |
| cell surface |
| postsynaptic density |
| growth cone |
| GO Term |
|---|
| preprotein binding |
| amyloid-beta binding |
| calmodulin binding |
| coreceptor activity |
| ubiquitin protein ligase binding |
| identical protein binding |
| protein-containing complex binding |
| small GTPase binding |
| death receptor activity |
| neurotrophin binding |
Sequence
MRRAGAACSAMDRLRLLLLLILGVSSGGAKETCSTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDNVTFSDVVSATEPCKPCTECLGLQSMSAPCVEADDAVCRCAYGYYQDEETGHCEACSVCEVGSGLVFSCQDKQNTVCEECPEGTYSDEANHVDPCLPCTVCEDTERQLRECTPWADAECEEIPGRWIPRSTPPEGSDSTAPSTQEPEVPPEQDLVPSTVADMVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEKLHSDSGISVDSQSLHDQQTHTQTASGQALKGDGNLYSSLPLTKREEVEKLLNGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWGAQDSATLDALLAALRRIQRADIVESLCSESTATSPV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Axonal growth inhibition (RHOA activation) | Rattus norvegicus |
| Axonal growth stimulation | Rattus norvegicus |
| NADE modulates death signalling | Rattus norvegicus |
| NF-kB is activated and signals survival | Rattus norvegicus |
| NFG and proNGF binds to p75NTR | Rattus norvegicus |
| NRIF signals cell death from the nucleus | Rattus norvegicus |
| Regulated proteolysis of p75NTR | Rattus norvegicus |
| p75NTR recruits signalling complexes | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:1686 | glaucoma | |
| DOID:3525 | middle cerebral artery infarction | |
| DOID:90 | degenerative disc disease |
