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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pro-epidermal growth factor
Summary
- UniProt ID
- P07522
- Gene Symbol
-
- Egf
- Organism
- Rattus norvegicus (Norway rat)
External Links
Annotation
- Keyword
-
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of calcium ion import |
| negative regulation of cholesterol efflux |
| positive regulation of protein localization to early endosome |
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| extracellular exosome |
Sequence
MLFSLTFLSVFLKITVLSVTAQQTRNCQSGPLERSGTTTYAAAGPPRFLIFLQGNSIFRINTDGTNHQQLVVDAGVSVVMDFHYKEERLYWVDLERQLLQRVFFNGSGQETVCKVDKNVSGLAINWIDGEILRTDRWKGVITVTDMNGNNSRVLLSSLKRPANILVDPTERLIFWSSVVTGNLHRADLGGMDVKTLLEAPERISVLILDILDKRLFWAQDGREGSHGYIHSCDYNGGSIHHIRHQARHDLLTMAIFGDKILYSALKEKAIWIADKHTGKNVVRVNLDPASVPPRELRVVHLHAQPGTENRAQASDSERCKQRRGQCLYSLSERDPNSDSSACAEGYTLSRDRKYCEDVNECALQNHGCTLGCENIPGSYYCTCPTGFVLLPDGKRCHELVACPGNRSECSHDCILTSDGPLCICPAGSVLGKDGKTCTGCSFSDNGGCSQICLPLSLASWECDCFPGYDLQLDRKSCAASMGPQPFLLFANSQDIRHMHFDGTDYKTLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANLDGSQRERRITEGVDTPEGLAVDWIGRRIYWTDSGKSVIEGSDLSGKHHQIIIKESISRPRGIAVHPKARRLFWTDTGMSPRIESSSLQGSDRTLIASSNLLEPSGIAIDYLTDTLYWCDTKLSVIEMADLDGSKRRRLTQNDVGHPFSLAVFEDHVWFSDWAIPSVIRVNKRTGQNRVRLRGSMLKPSSLVVVHPLAKPGADPCLHRNGGCEHICQESLGTAQCLCREGFVKAPDGKMCLTRKDDQILAGDNADLSKEVASLDNSPKAYVPDDDRTESSTLVAEIMVSGLNYEDDCGPGGCGSHAHCISEGEAAVCQCLKGFAGDGNLCSDIDECELGSSDCPPTSSRCINTEGGYVCQCSEGYEGDGIYCLDVDECQQGSHGCSENATCTNTEGGYNCTCAGCPSAPGLPCPDSTSPSLLGKDGCHWVRNSNTGCPPSYDGYCLNGGVCMYVESVDRYVCNCVIGYIGERCQHRDLRWWKLRHADYGQRHDITVVSVCVVALALLLLLGMWGTYYYRTRKQLSESSKKPSEESSSNVSSNGPDSSGAGVSSGPQPWFVVLEEHQQPKNGRLPAAGTNGAVVEAGLSSSL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 105 | N-linked (GlcNAc...) asparagine |
|
||
| 118 | N-linked (GlcNAc...) asparagine |
|
||
| 149 | N-linked (GlcNAc...) asparagine |
|
||
| 405 | N-linked (GlcNAc...) asparagine |
|
||
| 930 | N-linked (GlcNAc...) asparagine |
|
||
| 941 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Rattus norvegicus |
| Clathrin-mediated endocytosis | Rattus norvegicus |
| Downregulation of ERBB2 signaling | Rattus norvegicus |
| EGFR downregulation | Rattus norvegicus |
| EGFR interacts with phospholipase C-gamma | Rattus norvegicus |
| ERBB2 Activates PTK6 Signaling | Rattus norvegicus |
| ERBB2 Regulates Cell Motility | Rattus norvegicus |
| Extra-nuclear estrogen signaling | Rattus norvegicus |
| GAB1 signalosome | Rattus norvegicus |
| GRB2 events in EGFR signaling | Rattus norvegicus |
