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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neprilysin
Summary
- UniProt ID
- P07861
- Gene Symbol
-
- Mme
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Myristate
- Phosphoprotein
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| kidney development |
| placenta development |
| proteolysis |
| peptide metabolic process |
| learning or memory |
| protein processing |
| protein catabolic process |
| hormone catabolic process |
| positive regulation of neurogenesis |
| sensory perception of pain |
| GO Term |
|---|
| membrane raft |
| early endosome |
| trans-Golgi network |
| brush border |
| synaptic vesicle |
| cytoplasm |
| plasma membrane |
| membrane |
| axon |
| cytoplasmic vesicle |
Sequence
MGRSESQMDITDINAPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDASAEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLTLLPDIYGWPVASQNWEQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQHIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQRLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEINGKPFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYKEEEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSARQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFTWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 145 | N-linked (GlcNAc...) asparagine |
|
||
| 211 | N-linked (GlcNAc...) asparagine |
|
||
| 285 | N-linked (GlcNAc...) asparagine |
|
||
| 311 | N-linked (GlcNAc...) asparagine |
|
||
| 325 | N-linked (GlcNAc...) asparagine |
|
||
| 628 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Metabolism of Angiotensinogen to Angiotensins | Rattus norvegicus |
| Neutrophil degranulation | Rattus norvegicus |
| Physiological factors | Rattus norvegicus |
