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MIRAGE
Hepatic triacylglycerol lipase

Summary
UniProt ID
P07867
Gene Symbol
  • Lipc
Organism
Rattus norvegicus (Norway rat)
PubChem
P07867
SwissLipids
Re-Glyco
P07867
Annotation
Keyword
  • Glycoprotein
  • HDL
  • Heparin-binding
  • Hydrolase
  • Lipid degradation
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 6 entries
GO Term
early endosome
late endosome
cell surface
high-density lipoprotein particle
extracellular space
microvillus
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MGNHLQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTINCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRIGHVKSKTLFLITRAQSPFKVYHYQFKIQFINQMEKPMEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLLITLNKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTEPHYAGLIVKTIWVKAGETQQRMTFCPDNVDDLQLHPTQEKVFVKCDLKSKD
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
79 N-linked (GlcNAc...) asparagine
398 N-linked (GlcNAc...) asparagine
Feature
501001502002503003504004501494
50100150200250300350400450MGNHLQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTINCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRIGHVKSKTLFLITRAQSPFKVYHYQFKIQFINQMEKPMEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLLITLNKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTEPHYAGLIVKTIWVKAGETQQRMTFCPDNVDDLQLHPTQEKVFVKCDLKSKD
Domains & sites
PTM
ProtVista
50100150200250300350400450MGNHLQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTINCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRIGHVKSKTLFLITRAQSPFKVYHYQFKIQFINQMEKPMEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLLITLNKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTEPHYAGLIVKTIWVKAGETQQRMTFCPDNVDDLQLHPTQEKVFVKCDLKSKD
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Assembly of active LPL and LIPC lipase complexes Rattus norvegicus
Chylomicron clearance Rattus norvegicus
Disease
Displaying all 8 entries
DO ID Disease Name Source
DOID:1168 familial hyperlipidemia
DOID:1184 nephrotic syndrome
DOID:1312 focal segmental glomerulosclerosis
DOID:1459 hypothyroidism
DOID:2018 hyperinsulinism
DOID:2237 hepatitis
DOID:783 end stage renal disease
DOID:9970 obesity
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025