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Low affinity immunoglobulin gamma Fc region receptor II

Summary

UniProt ID

P08101

Gene Symbol

Fcgr2
Fcgr2b
Ly-17

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003308

GlyConnect

GlyGen

P08101

PubChem

P08101

RaftProt

P08101

Annotation

Keyword

Alternative splicing
Cell membrane
Cytoskeleton
Direct protein sequencing
Disulfide bond
Glycoprotein
IgG-binding protein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **11 - 20** of 36 in total

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GO Term
positive regulation of tumor necrosis factor production
negative regulation of neutrophil apoptotic process
negative regulation of phagocytosis
positive regulation of phagocytosis
antigen processing and presentation of exogenous peptide antigen via MHC class II
positive regulation of JNK cascade
regulation of long-term neuronal synaptic plasticity
negative regulation of type I hypersensitivity
negative regulation of inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to antigenic stimulus

Displaying **all 9** entries
GO Term
extracellular region
cytoskeleton
plasma membrane
membrane
cell body
external side of plasma membrane
cell surface
dendritic spine
recycling endosome

Displaying **all 3** entries
GO Term
IgG receptor activity
IgG binding
immunoglobulin binding

Annotation information from UniProt.

Sequence

MESNWTVHVFSRTLCHMLLWTAVLNLAAGTHDLPKAVVKLEPPWIQVLKEDTVTLTCEGTHNPGNSSTQWFHNGRSIRSQVQASYTFKATVNDSGEYRCQMEQTRLSDPVDLGVISDWLLLQTPQLVFLEGETITLRCHSWRNKLLNRISFFHNEKSVRYHHYSSNFSIPKANHSHSGDYYCKGSLGRTLHQSKPVTITVQGPKSSRSLPVLTIVAAVTGIAVAAIVIILVSLVYLKKKQVPALPGNPDHREMGETLPEEVGEYRQPSGGSVPVSPGPPSGLEPTSSSPYNPPDLEEAAKTEAENTITYSLLKHPEALDEETEHDYQNHI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	GlyTouCan ID	Source
4		G04657PL	GlyGen
65	N-linked (GlcNAc...) asparagine	G10486CT	GlycoProtDB UniProt GlyGen
92	N-linked (GlcNAc...) asparagine	G40574BA	GlycoProtDB UniProt GlyGen
166	N-linked (GlcNAc...) asparagine	G72747WU	GlycoProtDB UniProt GlyGen
173	N-linked (GlcNAc...) asparagine	G28541PG	GlycoProtDB UniProt GlyGen
		G69834CE G94531EZ G39595FH G50489VC G86696LV G86753CK G15169WU G45209NR G91413ZX G17689DH G22310AV G72667IM G75235YS G30460NZ G53752TA G84452RH G14994KB G68937TM G50757KG G85542KD G23863VK G78059CC G11870QZ G44617UT G46687AB G58667NI G29880MM G61334IA G45889JQ G94854LT G74724QE G82348BZ	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
FCGR activation	Mus musculus
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Mus musculus
Neutrophil degranulation	Mus musculus
Regulation of actin dynamics for phagocytic cup formation	Mus musculus
Role of phospholipids in phagocytosis	Mus musculus