GlyCosmos Portal

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Interleukin-3

Summary

UniProt ID

P08700

Gene Symbol

Organism

Homo sapiens (human)

External Links

PubChem: P08700
The Human Metabolome Database: HMDBP02287

Annotation

Keyword

3D-structure
Cytokine
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
embryonic hemopoiesis
immune response
cell-cell signaling
nervous system development
positive regulation of cell population proliferation
positive regulation of tyrosine phosphorylation of STAT protein
interleukin-3-mediated signaling pathway
positive regulation of peptidyl-tyrosine phosphorylation

Displaying **all 2** entries
GO Term
extracellular region
extracellular space

Displaying **all 3** entries
GO Term
growth factor activity
interleukin-3 receptor binding
cytokine activity

Annotation information from UniProt.

Sequence

MSRLPVLLLLQLLVRPGLQAPMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
34	N-linked (GlcNAc...) asparagine			UniProt
89	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Interleukin receptor SHC signaling	Homo sapiens
Interleukin-3, Interleukin-5 and GM-CSF signaling	Homo sapiens
RAF/MAP kinase cascade	Homo sapiens
RUNX1 regulates transcription of genes involved in interleukin signaling	Homo sapiens