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MIRAGE
Insulin-like receptor

Summary
UniProt ID
P09208
Gene Symbol
  • CG18402
  • Dir-a
  • IR
  • InR
  • Inr-a
Gene ID
42549
Organism
Drosophila melanogaster (fruit fly)
GlyGen
P09208
PubChem
P09208
Re-Glyco
P09208
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Cell membrane
  • Cell projection
  • Cleavage on pair of basic residues
  • Developmental protein
  • Differentiation
  • Disulfide bond
  • Glycoprotein
  • Growth regulation
  • Manganese
  • Metal-binding
  • Neurogenesis
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • SH3-binding
  • Signal
  • Transmembrane helix
  • Tyrosine-protein kinase
Gene Ontology (GO)
Displaying all 4 entries
GO Term
plasma membrane
axon
insulin receptor complex
growth cone membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MFNMPRGVTKSKSKRGKIKMENDMAAAATTTACTLGHICVLCRQEMLLDTCCCRQAVEAVDSPASSEEAYSSSNSSSCQASSEISAEEVWFLSHDDIVLCRRPKFDEVETTGKKRDVKCSGHQCSNECDDGSTKNNRQQRENFNIFSNCHNILRTLQSLLLLMFNCGIFNKRRRRQHQQQHHHHYQHHHQQHHQQHHQRQQANVSYTKFLLLLQTLAAATTRLSLSPKNYKQQQQLQHNQQLPRATPQQKQQEKDRHKCFHYKHNYSYSPGISLLLFILLANTLAIQAVVLPAHQQHLLHNDIADGLDKTALSVSGTQSRWTRSESNPTMRLSQNVKPCKSMDIRNMVSHFNQLENCTVIEGFLLIDLINDASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFPNLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEILAENETQLVVLTENGKEKECRLSKCPGEIRIEEGHDTTAIEGELNASCQLHNNRRLCWNSKLCQTKCPEKCRNNCIDEHTCCSQDCLGGCVIDKNGNESCISCRNVSFNNICMDSCPKGYYQFDSRCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGYQKSENKRMCEPCPGGKCDKECSSGLIDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELKYGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGPNQTVFIRKGGVFFHFNPKLCVSTINQLLPMLASKPKFFEKSDVGADSNGNRGSCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPYGNSTKSSDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELTNAESDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRNNNRDYCTEPLVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGMEFENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELDDVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSNDLHMNTEVNPFYASMQYIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQQNSSLDQPPESPIAMVDDQGSHLPFSLPSGFIASSTPDGQTVMATAFQNIPAAQGDISATYVVPDADALDGDRGYEIYDPSPKCAELPTSRSGSTGGGKLSGEQHLLPRKGRQPTIMSSSMPDDVIGGSSLQPSTASAGSSNASSHTGRPSLKKTVADSVRNKANFINRHLFNHKRTGSNASHKSNASNAPSTSSNTNLTSHPVAMGNLGTIESGGSGSAGSYTGTPRFYTPSATPGGGSGMAISDNPNYRLLDESIASEQATILTTSSPNPNYEMMHPPTSLVSTNPNYMPMNETPVQMAGVTISHNPNYQPMQAPLNARQSQSSSDEDNEQEEDDEDEDDDVDDEHVEHIKMERMPLSRPRQRALPSKTQPPRSRSVSQTRKSPTNPNSGIGATGAGNRSNLLKENWLRPASTPRPPPPNGFIGREA
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 22 in total
Position Description PubMed ID GlyTouCan ID Source
74 N-linked (GlcNAc...) asparagine
203
265
356 N-linked (GlcNAc...) asparagine
376 N-linked (GlcNAc...) asparagine
406 N-linked (GlcNAc...) asparagine
468 N-linked (GlcNAc...) asparagine
509 N-linked (GlcNAc...) asparagine
561 N-linked (GlcNAc...) asparagine
569 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Extra-nuclear estrogen signaling Drosophila melanogaster
Insulin receptor recycling Drosophila melanogaster
Insulin signaling pathway Drosophila melanogaster
Disease
Displaying all 8 entries
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:162 cancer
DOID:3070 high grade glioma
DOID:4194 glucose metabolism disease
DOID:535 sleep disorder
DOID:9351 diabetes mellitus
DOID:9352 type 2 diabetes mellitus
DOID:9743 diabetic neuropathy
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025