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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Intestinal-type alkaline phosphatase
Summary
- UniProt ID
- P09923
- Gene Symbol
-
- ALPI
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Hydrolase
- Magnesium
- Metal-binding
- Reference proteome
- Signal
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| dephosphorylation |
| GO Term |
|---|
| side of membrane |
| extracellular region |
| plasma membrane |
| GO Term |
|---|
| magnesium ion binding |
| alkaline phosphatase activity |
| zinc ion binding |
| protease binding |
Sequence
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 141 | N-linked (GlcNAc...) asparagine | |||
| 268 | N-linked (GlcNAc...) asparagine | |||
| 429 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G08918WF
G47644PP
G41247ZX
G92275SC
G43223CG
G00912UN
G87661QW
G83646BJ
G27058EU
G41071NU
G70619PT
G59626AS
G80920RR
G42124LM
G62765YT
G31544HA
G31991IV
G75308SV
G63889NK
G90093AU
G18938DW
G47012YE
G72797UR
G86357DX
G20425TQ
G29857RC
G23863VK
G78059CC
G36191CD
G50045TK
G23453IV
G69411IG
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Digestion | Homo sapiens |
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
| Synthesis of PA | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13198 | endemic goiter | |
| DOID:13200 | substernal goiter | |
| DOID:1324 | lung cancer | |
| DOID:1325 | bronchus cancer | |
| DOID:14227 | azoospermia | |
| DOID:14261 | fragile X syndrome | |
| DOID:1443 | cerebral degeneration | |
| DOID:14525 | Reye syndrome | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer |
