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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Leukotriene A-4 hydrolase
Summary
- UniProt ID
- P09960
- Gene Symbol
-
- LTA4H
- LTA4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Leukotriene biosynthesis
- Lipid metabolism
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular exosome |
| tertiary granule lumen |
| cytosol |
| nucleoplasm |
| extracellular region |
| nucleus |
| ficolin-1-rich granule lumen |
Sequence
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 42 |
|
|||
| 45 |
|
|||
| 531 |
|
G49108TO
G07755XJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Biosynthesis of D-series resolvins | Homo sapiens |
| Biosynthesis of E-series 18(R)-resolvins | Homo sapiens |
| Biosynthesis of E-series 18(S)-resolvins | Homo sapiens |
| Biosynthesis of aspirin-triggered D-series resolvins | Homo sapiens |
| Biosynthesis of protectins | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1024 | leprosy | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050456 | Buruli ulcer disease | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0060192 | Crohn's colitis | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0110892 | inflammatory bowel disease 1 | |
| DOID:0111344 | myeloproliferative disorder with eosinophilia | |
| DOID:10283 | prostate cancer |
