Synthesis of Leukotrienes (LT) and Eoxins (EX)

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ALOX5:Ca2+:Fe2+ADPATPH+p-S272-ALOX5:Ca2+:Fe2+AA5S-HpETEO2ALOX5:FLAP:LTC4SALOX5:ALOX5 inhibitorsALOX5 inhibitorsH2OLTA4LTB4TPNTPNH12-oxoLTB420OH-LTB420cho-LTB420cooh-LTB418cooh-LTB4LTC4GSHPiLTC46t/6t,12epi-LTB4EXA4EXC4L-GluEXD4GlyEXE4L-GluH2OLTD4GlyLTE4
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 6 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P09960 Leukotriene A-4 hydrolase
  • LTA4
  • LTA4H
view
P16444 Dipeptidase 1
  • DPEP1
  • MDP
  • RDP
view
P19440 Glutathione hydrolase 1 proenzyme
  • GGT
  • GGT1
view
P33527 Multidrug resistance-associated protein 1
  • ABCC1
  • MRP
  • MRP1
view
P36269 Glutathione hydrolase 5 proenzyme
  • GGT5
  • GGTLA1
view
Q9H4A9 Dipeptidase 2
  • DPEP2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025