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MIRAGE
Mitogen-activated protein kinase kinase kinase 7
Summary
- UniProt ID
- P0C8E4
- Gene Symbol
-
- Map3k7
- Gene ID
- 313121
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Apoptosis
- Cell membrane
- Cytoplasm
- Isopeptide bond
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Stress response
- Transcription regulation
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| postsynaptic density |
| ATAC complex |
| cytoplasm |
| plasma membrane |
| cytosol |
| GO Term |
|---|
| immune response |
| negative regulation of gene expression |
| defense response to bacterium |
| positive regulation of cell cycle |
| positive regulation of autophagy |
Sequence
MSTASAASSSSSSSASEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSDSGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIVATTAYTKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPARSLPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 471 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| TNFR1-induced NF-kappa-B signaling pathway | Rattus norvegicus |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | Rattus norvegicus |
| Ub-specific processing proteases | Rattus norvegicus |
| activated TAK1 mediates p38 MAPK activation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2349 | arteriosclerosis |
