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Laminin subunit gamma-1

Summary

UniProt ID

P11047

Gene Symbol

LAMC1
LAMB2

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011483

GlyConnect

1444

GlyGen

P11047

PubChem

P11047

The O-GlcNAc Database

P11047

RaftProt

P11047

O-GlcNAcAtlas

P11047

Annotation

Keyword

3D-structure
Basement membrane
Cell adhesion
Coiled coil
Disulfide bond
Glycoprotein
Laminin EGF-like domain
Phosphoprotein
Reference proteome
Repeat
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 13 in total

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GO Term
cell adhesion
hemidesmosome assembly
regulation of basement membrane organization
positive regulation of integrin-mediated signaling pathway
endoderm development
cell migration
positive regulation of cell adhesion
positive regulation of epithelial cell proliferation
maintenance of blood-brain barrier
positive regulation of muscle cell differentiation

Displaying **all 10** entries
GO Term
endoplasmic reticulum lumen
extracellular region
basement membrane
extracellular space
collagen-containing extracellular matrix
laminin-10 complex
laminin-11 complex
protein complex involved in cell-matrix adhesion
extracellular exosome
laminin-1 complex

Displaying 1 entry
GO Term
extracellular matrix structural constituent

Annotation information from UniProt.

Sequence

MRGSHRAAPALRPRGRLWPVLAVLAAAAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 24 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
60	N-linked (GlcNAc...) asparagine			UniProt GlyGen
134	N-linked (GlcNAc...) asparagine			UniProt GlyGen
576	N-linked (GlcNAc...) asparagine		G43089EG G70232NH G08918WF G00912UN G48414YA G84452RH G41071NU G46902YN G72747WU G70619PT G06356OH G59626AS G01650EU G80920RR G65184UU G90659AW G37399XV G62765YT G72790NZ G10486CT G28541PG G95865ZB G31852PQ G49955PK G72787SB G39446WN G41247ZX G57776ZU G02815KT G06110VR G92050GC	UniProt GlyGen GlyConnect
650	N-linked (GlcNAc...) asparagine	12754519 19159218	G71051TA G33791AF G58087IP G83646BJ G83460ZZ G06356OH G59626AS G72398FA G92406TI G01650EU G23294PN G70101JE G80920RR G37399XV G62765YT G64527OM G10486CT G28541PG G05724UK G31852PQ G39446WN G39188ZX G41247ZX G57776ZU G02815KT G06110VR G92050GC	UniProt GlyGen GlyConnect
1022	N-linked (GlcNAc...) asparagine		G06247RL G45395BF G85554PZ G43223CG G40574BA G08918WF G00912UN G48414YA G27915IV G70441OD G87661QW G83646BJ G76295SF G46691LC G04657PL G27058EU G84452RH G43769HG G83460ZZ G60033FS G41071NU G07755XJ G86182NS G70619PT G06356OH G59626AS G01650EU G25079LO G80920RR G65184UU G42124LM G02886BB G90659AW G45504EY G83633GK G62765YT G23432EQ G72790NZ G95177YH G10486CT G50045TK G05049YU G28541PG G18647XP G95865ZB G31852PQ G49955PK G72787SB G23719VF G39446WN G11314AS G41247ZX G35029YA G57776ZU G02815KT G57317CE G92050GC G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
1107	N-linked (GlcNAc...) asparagine	16335952 19159218	G57888GL G35541EV G93718GY G57776ZS G44753VC G68490OW G86880BF G30970QQ G80479JV G20528HD G79666IR G92135MA G45395BF G07246CJ G40926MX G43223CG G08918WF G00912UN G27915IV G92551JA G70441OD G87661QW G76295SF G27126ED G08293MJ G27058EU G84452RH G43769HG G37509XX G60033FS G41071NU G07755XJ G70619PT G06356OH G59626AS G01650EU G23294PN G70101JE G80920RR G34730YF G67324HN G65184UU G42124LM G02886BB G90659AW G62765YT G64527OM G47644PP G72790NZ G95177YH G10486CT G50045TK G05049YU G28541PG G85269DF G95865ZB G31852PQ G49955PK G72787SB G23719VF G39446WN G11314AS G41247ZX G35029YA G57776ZU G36379GD G02815KT G57317CE G92050GC G28681TP	GlycoProtDB UniProt GlyGen GlyConnect
1109			G49108TO	GlyGen The O-GlcNAc Database
1115			G49108TO	The O-GlcNAc Database
1161	N-linked (GlcNAc...) asparagine	16335952	G12270AG G11101UV	GlycoProtDB UniProt GlyGen
1170			G53434XO G58001LT G43417UB	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Degradation of the extracellular matrix	Homo sapiens
ECM proteoglycans	Homo sapiens
EGR2 and SOX10-mediated initiation of Schwann cell myelination	Homo sapiens
L1CAM interactions	Homo sapiens
Laminin interactions	Homo sapiens
MET activates PTK2 signaling	Homo sapiens
Non-integrin membrane-ECM interactions	Homo sapiens
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens

Human Protein Atlas

ENSG00000135862

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements