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Bone morphogenetic protein 2

Summary

UniProt ID

P12643

Gene Symbol

BMP2
BMP2A

Organism

Homo sapiens (human)

External Links

GlycoProtDB: GPDB0011505
GlyGen: P12643
PubChem: P12643
The Human Metabolome Database: HMDBP02308

Annotation

Keyword

3D-structure
Chondrogenesis
Cleavage on pair of basic residues
Cytokine
Developmental protein
Differentiation
Disease variant
Disulfide bond
Dwarfism
Glycoprotein
Growth factor
Osteogenesis
Pharmaceutical
Phosphoprotein
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **51 - 60** of 98 in total

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GO Term
positive regulation of astrocyte differentiation
inner ear development
cardiac muscle cell differentiation
corticotropin hormone secreting cell differentiation
thyroid-stimulating hormone-secreting cell differentiation
bone development
lung vasculature development
positive regulation of cartilage development
cellular response to organic cyclic compound
mesenchymal cell proliferation involved in ureteric bud development

Displaying **all 5** entries
GO Term
extracellular region
extracellular space
intracellular membrane-bounded organelle
cell surface
BMP receptor complex

Displaying **all 7** entries
GO Term
signaling receptor binding
protein serine/threonine kinase activator activity
cytokine activity
phosphatase activator activity
growth factor activity
co-receptor binding
BMP receptor binding

Annotation information from UniProt.

Sequence

MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
86			G57321FI	GlyGen
135	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
163	N-linked (GlcNAc...) asparagine		G80920RR	GlycoProtDB UniProt GlyGen
164	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen
200	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen
338	N-linked (GlcNAc...) (high mannose) asparagine	9265423		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Molecules associated with elastic fibres	Homo sapiens
Regulation of RUNX2 expression and activity	Homo sapiens
Signaling by BMP	Homo sapiens
Transcriptional regulation by RUNX2	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements