Bone morphogenetic protein 4

Summary
UniProt ID
P12644
Gene Symbol
  • BMP2B
  • BMP4
  • DVR4
Gene ID
652
Organism
Homo sapiens (human)
PubChem
P12644
The Human Metabolome Database
HMDBP14532
Re-Glyco
P12644
Annotation
Keyword
  • Chondrogenesis
  • Cleavage on pair of basic residues
  • Cytokine
  • Developmental protein
  • Differentiation
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Growth factor
  • Microphthalmia
  • Osteogenesis
  • Phosphoprotein
  • Reference proteome
  • Signal
Gene Ontology (GO)
Sequence
MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
Glycosylation Sites
Displaying all 4 entries
Position Description PubMed ID GlyTouCan ID Source
143 N-linked (GlcNAc...) asparagine
208 N-linked (GlcNAc...) asparagine
350 N-linked (GlcNAc...) asparagine
365 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying entries 1 - 10 of 11 in total
DO ID Disease Name Source
DOID:0050591 tooth agenesis
DOID:0060887 ossification of the posterior longitudinal ligament of spine
DOID:0080205 CAKUT
DOID:0080207 CAKUT2
DOID:0080404 orofacial cleft 11
DOID:0111805 syndromic microphthalmia 6
DOID:12185 otosclerosis
DOID:1222 cartilage disease
DOID:1882 atrial heart septal defect
DOID:1909 melanoma

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025