5-aminolevulinate synthase, non-specific, mitochondrial

Summary
UniProt ID
P13196
Gene Symbol
  • ALAS1
  • ALAS3
  • ALASH
Organism
Homo sapiens (human)
External Links
GlyGen
P13196
PubChem
P13196
The Human Metabolome Database
HMDBP00022
The O-GlcNAc Database
P13196
RaftProt
P13196
Annotation
Keyword
  • Acyltransferase
  • Alternative splicing
  • Heme biosynthesis
  • Hydroxylation
  • Mitochondrion inner membrane
  • Pyridoxal phosphate
  • Reference proteome
  • Transit peptide
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
250
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Heme biosynthesis Homo sapiens
Mitochondrial protein degradation Homo sapiens
PPARA activates gene expression Homo sapiens
Transcriptional activation of mitochondrial biogenesis Homo sapiens

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024