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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glypican-3
Summary
- UniProt ID
- P13265
- Gene Symbol
-
- Gpc3
- Organism
- Rattus norvegicus (Norway rat)
External Links
- PubChem
- P13265
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- GPI-anchor
- Heparan sulfate
- Phosphoprotein
- Protease inhibitor
- Pyrrolidone carboxylic acid
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| side of membrane |
| lysosome |
| plasma membrane |
| collagen-containing extracellular matrix |
| GO Term |
|---|
| peptidyl-dipeptidase inhibitor activity |
Sequence
MAGTVRTACLLVAMLLGLGCLGQAQPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQMMNPGLPESVLDINECLRGARRDLKVFGSFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVARVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVVDKSLDEEGLESGDCGDDEDECIGSSGDGMMKVKNQLRFLAELAYDLDVDDAPGNKQHGNQKDNEITTSHSVGNMPSPLKILISVAIYVACFFSWCTDLPCPCLCCPAAPCGPPT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 123 | N-linked (GlcNAc...) asparagine |
|
||
| 240 | N-linked (GlcNAc...) asparagine |
|
||
| 417 | N-linked (GlcNAc...) asparagine |
|
||
| 494 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 508 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Rattus norvegicus |
| HS-GAG biosynthesis | Rattus norvegicus |
| HS-GAG degradation | Rattus norvegicus |
| Post-translational protein phosphorylation | Rattus norvegicus |
| Regulation of IGF Activity by IGFBP | Rattus norvegicus |
| Retinoid metabolism and transport | Rattus norvegicus |
