HS-GAG degradation

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HS/HPIN-PGsHS/HPIN-PGsH2OHS core proteinsHeparan sulfate chain(1)Hpse2HPSE2:HS/HPIN-PGsL-Iduronic acidHeparan sulfate chain(2)Heparan sulfate chain(3)SO4(2-)Heparan sulfate chain(4)CoA-SHAc-CoAGlcNAcHeparan sulfate chain(5)Heparan sulfate chain(6)Heparan sulfate chain(7)Heparan chain(1)Heparan chain(2)CS/HS precursorGlcAlinker chain(2)D-xyloseGal
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 10 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P06760 Beta-glucuronidase
  • Gus
  • Gusb
view
P13265 Glypican-3
  • Gpc3
view
P25304 Agrin
  • Agrin
  • Agrn
view
P26260 Syndecan-1
  • Sdc1
  • Synd1
view
P33671 Syndecan-3
  • Sdc3
  • Synd3
view
P34900 Syndecan-2
  • Hspg1
  • Sdc2
  • Synd2
view
P34901 Syndecan-4
  • Sdc4
  • Synd4
view
P35053 Glypican-1
  • Gpc1
view
P51653 Glypican-2
  • Gpc2
view
Q71RP1 Heparanase
  • Hep
  • Hpse
view
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_001368 P06760 Beta-glucuronidase view
Displaying all 2 entries
GlyTouCan ID KEGG GLYCAN ChEBI Pathway Viewer
G01550VL
view
G09546QO
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025