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Plasma kallikrein
Summary
- UniProt ID
- P14272
- Gene Symbol
-
- Klk3
- Klkb1
- Pk
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Direct protein sequencing
- Disulfide bond
- Fibrinolysis
- Glycoprotein
- Inflammatory response
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| GO Term |
|---|
| liver regeneration |
| positive regulation of fibrinolysis |
| inflammatory response |
| blood coagulation |
| fibrinolysis |
| plasminogen activation |
| GO Term |
|---|
| serine-type endopeptidase activity |
Sequence
MILFKQVGYFVSLFATVSCGCLSQLYANTFFRGGDLAAIYTPDAQHCQKMCTFHPRCLLFSFLAVSPTKETDKRFGCFMKESITGTLPRIHRTGAISGHSLKQCGHQLSACHQDIYEGLDMRGSNFNISKTDSIEECQKLCTNNIHCQFFTYATKAFHRPEYRKSCLLKRSSSGTPTSIKPVDNLVSGFSLKSCALSEIGCPMDIFQHFAFADLNVSQVVTPDAFVCRTVCTFHPNCLFFTFYTNEWETESQRNVCFLKTSKSGRPSPPIIQENAVSGYSLFTCRKARPEPCHFKIYSGVAFEGEELNATFVQGADACQETCTKTIRCQFFTYSLLPQDCKAEGCKCSLRLSTDGSPTRITYEAQGSSGYSLRLCKVVESSDCTTKINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCFDGIPYPDVWRIYGGILNLSEITNKTPFSSIKELIIHQKYKMSEGSYDIALIKLQTPLNYTEFQKPICLPSKADTNTIYTNCWVTGWGYTKERGETQNILQKATIPLVPNEECQKKYRDYVITKQMICAGYKEGGIDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKEQPGVYTKVAEYIDWILEKIQSSKERALETSPA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 127 | N-linked (GlcNAc...) asparagine |
|
||
| 215 | N-linked (GlcNAc...) asparagine |
|
||
| 308 | N-linked (GlcNAc...) asparagine |
|
||
| 396 | N-linked (GlcNAc...) asparagine |
|
||
| 453 | N-linked (GlcNAc...) asparagine |
|
||
| 494 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Rattus norvegicus |
| Intrinsic Pathway of Fibrin Clot Formation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease |
