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Insulin receptor-related protein

Summary

UniProt ID

P14616

Gene Symbol

INSRR
IRR

Organism

Homo sapiens (human)

External Links

PubChem: P14616
The Human Metabolome Database: HMDBP01245

Annotation

Keyword

3D-structure
ATP-binding
Cleavage on pair of basic residues
Disulfide bond
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
transmembrane receptor protein tyrosine kinase signaling pathway
actin cytoskeleton organization
cellular response to alkaline pH
male sex determination
protein autophosphorylation

Displaying **all 4** entries
GO Term
plasma membrane
insulin receptor complex
axon
receptor complex

Displaying **all 5** entries
GO Term
transmembrane receptor protein tyrosine kinase activity
insulin receptor activity
insulin receptor substrate binding
ATP binding
phosphatidylinositol 3-kinase binding

Annotation information from UniProt.

Sequence

MAVPSLWPWGACLPVIFLSLGFGLDTVEVCPSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPALGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTARGECCHTECLGGCSQPEDPRACVACRHLYFQGACLWACPPGTYQYESWRCVTAERCASLHSVPGRASTFGIHQGSCLAQCPSGFTRNSSSIFCHKCEGLCPKECKVGTKTIDSIQAAQDLVGCTHVEGSLILNLRQGYNLEPQLQHSLGLVETITGFLKIKHSFALVSLGFFKNLKLIRGDAMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLASLKPWTQYAVFVRAITLTTEEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNLTYYLVLWQRLAEDGDLYLNDYCHRGLRLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYILGPEEEDAGGLHVLLTATPVGLTLLIVLAALGFFYGKKRNRTLYASVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEELRPSFRLLSFYYSPECRGARGSLPTTDAEPDSSPTPRDCSPQNGGPGH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	Source
47	N-linked (GlcNAc...) asparagine	UniProt
311	N-linked (GlcNAc...) asparagine	UniProt
411	N-linked (GlcNAc...) asparagine	UniProt
492	N-linked (GlcNAc...) asparagine	UniProt
528	N-linked (GlcNAc...) asparagine	UniProt
616	N-linked (GlcNAc...) asparagine	UniProt
634	N-linked (GlcNAc...) asparagine	UniProt
756	N-linked (GlcNAc...) asparagine	UniProt
885	N-linked (GlcNAc...) asparagine	UniProt
898	N-linked (GlcNAc...) asparagine	UniProt