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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Interleukin-1 receptor type 1
Summary
- UniProt ID
- P14778
- Gene Symbol
-
- IL1R1
- IL1R
- IL1RA
- IL1RT1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P14778
- PubChem
- P14778
- The Human Metabolome Database
- HMDBP12410
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Immunoglobulin domain
- Inflammatory response
- NAD
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| membrane |
| external side of plasma membrane |
Sequence
MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEIDVRPCPLNPNEHKGTITWYKDDSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSSYCLRIKISAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQWYKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEENKPTRPVIVSPANETMEVDLGSQIQLICNVTGQLSDIAYWKWNGSVIDEDDPVLGEDYYSVENPANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKHMIGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVGEGSTSDCDIFVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRLIIILVRETSGFSWLGGSSEEQIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQKHGAIRWSGDFTQGPQSAKTRFWKNVRYHMPVQRRSPSSKHQLLSPATKEKLQREAHVPLG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 100 | N-linked (GlcNAc...) asparagine |
|
||
| 193 | N-linked (GlcNAc...) asparagine | |||
| 233 | N-linked (GlcNAc...) asparagine |
|
||
| 249 | N-linked (GlcNAc...) asparagine |
|
||
| 263 | N-linked (GlcNAc...) asparagine |
|
||
| 297 | N-linked (GlcNAc...) asparagine |
|
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-1 signaling | Homo sapiens |
| Interleukin-10 signaling | Homo sapiens |
| Potential therapeutics for SARS | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14268 | sclerosing cholangitis | |
| DOID:14269 | suppurative cholangitis | |
| DOID:14270 | ascending cholangitis | |
| DOID:14286 | neurogenic arthropathy | |
| DOID:1443 | cerebral degeneration | |
| DOID:14525 | Reye syndrome | |
| DOID:1470 | major depressive disorder | |
| DOID:1474 | aggressive periodontitis | |
| DOID:1520 | colon carcinoma | |
| DOID:1574 | alcohol use disorder |
