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MIRAGE
5-hydroxytryptamine receptor 2A

Summary
UniProt ID
P14842
Gene Symbol
  • Htr2
  • Htr2a
Gene ID
29595
Organism
Rattus norvegicus (Norway rat)
PubChem
P14842
Re-Glyco
P14842
Annotation
Keyword
  • 3D-structure
  • Behavior
  • Cell membrane
  • Cell projection
  • Cytoplasmic vesicle
  • Disulfide bond
  • G-protein coupled receptor
  • Glycoprotein
  • Phosphoprotein
  • Reference proteome
  • Synapse
  • Transmembrane helix
Gene Ontology (GO)
Displaying entries 1 - 10 of 13 in total
GO Term
plasma membrane
axon
dendrite
cytoplasmic vesicle
glutamatergic synapse
neuronal cell body
postsynaptic membrane
neurofilament
caveola
presynaptic membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
8 N-linked (GlcNAc...) asparagine
38 N-linked (GlcNAc...) asparagine
44 N-linked (GlcNAc...) asparagine
51 N-linked (GlcNAc...) asparagine
54 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
G alpha (q) signalling events Rattus norvegicus
Serotonin receptors Rattus norvegicus
Disease
Displaying entries 1 - 10 of 13 in total
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0050742 nicotine dependence
DOID:0060001 withdrawal disorder
DOID:10652 Alzheimer's disease
DOID:1574 alcohol use disorder
DOID:1596 depressive disorder
DOID:2537 inflammatory and toxic neuropathy
DOID:4195 hyperglycemia
DOID:4989 pancreatitis
DOID:5419 schizophrenia
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025