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5-hydroxytryptamine receptor 2A

Summary

UniProt ID

P14842

Gene Symbol

Htr2a
Htr2

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P14842

Annotation

Keyword

3D-structure
Behavior
Cell membrane
Cell projection
Cytoplasmic vesicle
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Synapse
Transmembrane helix

Gene Ontology (GO)

Displaying entries **21 - 30** of 40 in total

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GO Term
positive regulation of execution phase of apoptosis
positive regulation of DNA biosynthetic process
positive regulation of heat generation
release of sequestered calcium ion into cytosol
negative regulation of potassium ion transport
phosphatidylinositol 3-kinase/protein kinase B signal transduction
behavioral response to cocaine
glycolytic process
response to xenobiotic stimulus
positive regulation of phosphatidylinositol biosynthetic process

Displaying entries **1 - 10** of 12 in total

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GO Term
plasma membrane
axon
cytoplasmic vesicle
postsynaptic membrane
dendrite
neuronal cell body
G protein-coupled serotonin receptor complex
glutamatergic synapse
dendritic shaft
caveola

Displaying **all 8** entries
GO Term
G protein-coupled serotonin receptor activity
protein-containing complex binding
serotonin binding
protein tyrosine kinase activator activity
neurotransmitter receptor activity
identical protein binding
Gq/11-coupled serotonin receptor activity
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding

Annotation information from UniProt.

Sequence

MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
8	N-linked (GlcNAc...) asparagine	UniProt
38	N-linked (GlcNAc...) asparagine	UniProt
44	N-linked (GlcNAc...) asparagine	UniProt
51	N-linked (GlcNAc...) asparagine	UniProt
54	N-linked (GlcNAc...) asparagine	UniProt