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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
Summary
- UniProt ID
- P15509
- Gene Symbol
-
- CSF2RA
- CSF2R
- CSF2RY
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| receptor complex |
| granulocyte macrophage colony-stimulating factor receptor complex |
| external side of plasma membrane |
| GO Term |
|---|
| cytokine receptor activity |
| cytokine binding |
| signaling receptor activity |
Sequence
MLLLVTSLLLCELPHPAFLLIPEKSDLRTVAPASSLNVRFDSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNTSQRGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILNWSSWSEAIEFGSDDGNLGSVYIYVLLIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKDKLNDNHEVEDEIIWEEFTPEEGKGYREEVLTVKEIT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 46 | N-linked (GlcNAc...) asparagine | |||
| 54 | N-linked (GlcNAc...) asparagine | |||
| 99 | N-linked (GlcNAc...) asparagine |
|
||
| 123 | N-linked (GlcNAc...) asparagine |
|
||
| 135 | N-linked (GlcNAc...) asparagine | |||
| 182 | N-linked (GlcNAc...) asparagine | |||
| 195 | N-linked (GlcNAc...) asparagine | |||
| 223 | N-linked (GlcNAc...) asparagine | |||
| 229 | N-linked (GlcNAc...) asparagine | |||
| 272 | N-linked (GlcNAc...) asparagine |
G12270AG
G76868JS
G49955PK
G23719VF
G62765YT
G31852PQ
G41247ZX
G80920RR
G28541PG
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective CSF2RA causes SMDP4 | Homo sapiens |
| Defective CSF2RB causes SMDP5 | Homo sapiens |
| Interleukin receptor SHC signaling | Homo sapiens |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| Surfactant metabolism | Homo sapiens |
