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Coagulation factor IX
Summary
- UniProt ID
- P16296
- Gene Symbol
-
- Cf9
- F9
- Gene ID
- 24946
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Blood coagulation
- Calcium
- Disulfide bond
- EGF-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydroxylation
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Serine protease
- Signal
- Sulfation
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| GO Term |
|---|
| proteolysis |
| blood coagulation |
| zymogen activation |
| GO Term |
|---|
| peptidase activity |
| serine-type endopeptidase activity |
| calcium ion binding |
| metal ion binding |
| endopeptidase activity |
Sequence
MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 78 | O-linked (GalNAc...) threonine |
|
||
| 92 | O-linked (Glc...) serine |
|
||
| 199 | O-linked (GalNAc...) threonine; alternate |
|
||
| 208 | N-linked (GlcNAc...) asparagine |
|
||
| 214 | N-linked (GlcNAc...) asparagine |
|
||
| 216 | O-linked (GalNAc...) threonine |
|
||
| 226 | O-linked (GalNAc...) threonine |
|
||
| 307 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Extrinsic Pathway of Fibrin Clot Formation | Rattus norvegicus |
| Gamma-carboxylation of protein precursors | Rattus norvegicus |
| Intrinsic Pathway of Fibrin Clot Formation | Rattus norvegicus |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Rattus norvegicus |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | Rattus norvegicus |
