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MIRAGE
Interferon alpha/beta receptor 1

Summary
UniProt ID
P17181
Gene Symbol
  • IFNAR
  • IFNAR1
Gene ID
3454
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P17181
PubChem
P17181
Re-Glyco
P17181
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • Endosome
  • Glycoprotein
  • Isopeptide bond
  • Lysosome
  • Palmitate
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
  • Ubl conjugation
Gene Ontology (GO)
Displaying all 3 entries
GO Term
lysosome
plasma membrane
late endosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFALPFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 13 in total
Position Description PubMed ID GlyTouCan ID Source
50 N-linked (GlcNAc...) asparagine
58 N-linked (GlcNAc...) asparagine
81 N-linked (GlcNAc...) asparagine
88 N-linked (GlcNAc...) asparagine
110 N-linked (GlcNAc...) asparagine
172 N-linked (GlcNAc...) asparagine
254 N-linked (GlcNAc...) asparagine
313 N-linked (GlcNAc...) asparagine
314 N-linked (GlcNAc...) asparagine
376 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Evasion by RSV of host interferon responses Homo sapiens
Interferon alpha/beta signaling Homo sapiens
Potential therapeutics for SARS Homo sapiens
Regulation of IFNA/IFNB signaling Homo sapiens
SARS-CoV-2 activates/modulates innate and adaptive immune responses Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:1883 hepatitis C
DOID:612 primary immunodeficiency disease
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025