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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Synapsin-1
Summary
- UniProt ID
- P17600
- Gene Symbol
-
- SYN1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Actin-binding
- Alternative splicing
- Cell projection
- Cytoplasmic vesicle
- Disease variant
- Epilepsy
- Glycoprotein
- Golgi apparatus
- Intellectual disability
- Methylation
- Phosphoprotein
- Reference proteome
- Repeat
- Synapse
- Gene Ontology (GO)
| GO Term |
|---|
| synaptic vesicle |
| postsynaptic density |
| synaptic vesicle membrane |
| presynaptic active zone |
| Schaffer collateral - CA1 synapse |
| extrinsic component of synaptic vesicle membrane |
| synaptonemal complex |
| Golgi apparatus |
| cytoskeleton |
| axon |
| GO Term |
|---|
| cytoskeletal protein-membrane anchor activity |
| actin binding |
| ATP binding |
| protein kinase binding |
| identical protein binding |
| calcium-dependent protein binding |
Sequence
MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 43 |
|
|
||
| 55 | O-linked (GlcNAc) serine |
|
||
| 87 | O-linked (GlcNAc) threonine | |||
| 96 | O-linked (GlcNAc) serine |
|
||
| 103 | O-linked (GlcNAc) serine |
|
||
| 261 | O-linked (GlcNAc) serine |
|
||
| 262 |
|
|||
| 263 |
|
|||
| 432 | O-linked (GlcNAc) serine; alternate |
|
||
| 526 | O-linked (GlcNAc) threonine |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Dopamine Neurotransmitter Release Cycle | Homo sapiens |
| Sensory processing of sound by inner hair cells of the cochlea | Homo sapiens |
| Serotonin Neurotransmitter Release Cycle | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
