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Neuronal acetylcholine receptor subunit beta-2

Summary

UniProt ID

P17787

Gene Symbol

CHRNB2

Organism

Homo sapiens (human)

External Links

PubChem: P17787
The Human Metabolome Database: HMDBP12044

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Disulfide bond
Epilepsy
Glycoprotein
Ligand-gated ion channel
Postsynaptic cell membrane
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 39 in total

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GO Term
response to nicotine
positive regulation of B cell proliferation
regulation of synaptic transmission, dopaminergic
positive regulation of dopamine secretion
regulation of dopamine metabolic process
negative regulation of action potential
regulation of dendrite morphogenesis
regulation of synapse assembly
synaptic transmission involved in micturition
response to acetylcholine

Displaying **all 10** entries
GO Term
synapse
plasma membrane
membrane
neuron projection
presynaptic membrane
postsynaptic specialization membrane
cholinergic synapse
plasma membrane raft
acetylcholine-gated channel complex
external side of plasma membrane

Displaying **all 7** entries
GO Term
ligand-gated monoatomic ion channel activity
protein-containing complex binding
heterocyclic compound binding
acetylcholine receptor activity
acetylcholine-gated monoatomic cation-selective channel activity
acetylcholine binding
quaternary ammonium group binding

Annotation information from UniProt.

Sequence

MARRCGPVALLLGFGLLRLCSGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQRLRLRRRQREREGAGALFFREAPGADSCTCFVNRASVQGLAGAFGAEPAPVAGPGRSGEPCGCGLREAVDGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTTTTFLHSDHSAPSSK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
51	N-linked (GlcNAc...) asparagine	UniProt
168	N-linked (GlcNAc...) asparagine	UniProt
485	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Highly calcium permeable nicotinic acetylcholine receptors	Homo sapiens
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Homo sapiens
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Homo sapiens