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MIRAGE
Neuronal acetylcholine receptor subunit beta-2

Summary
UniProt ID
P17787
Gene Symbol
  • CHRNB2
Gene ID
1141
Organism
Homo sapiens (human)
PubChem
P17787
The Human Metabolome Database
HMDBP12044
Re-Glyco
P17787
Annotation
Keyword
  • 3D-structure
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • Epilepsy
  • Glycoprotein
  • Ligand-gated ion channel
  • Postsynaptic cell membrane
  • Receptor
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 10 entries
GO Term
plasma membrane
membrane
neuron projection
synapse
cholinergic synapse
postsynaptic specialization membrane
external side of plasma membrane
acetylcholine-gated channel complex
presynaptic membrane
plasma membrane raft
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MARRCGPVALLLGFGLLRLCSGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQRLRLRRRQREREGAGALFFREAPGADSCTCFVNRASVQGLAGAFGAEPAPVAGPGRSGEPCGCGLREAVDGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTTTTFLHSDHSAPSSK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
51 N-linked (GlcNAc...) asparagine
168 N-linked (GlcNAc...) asparagine
485 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Highly calcium permeable nicotinic acetylcholine receptors Homo sapiens
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Homo sapiens
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0060681 autosomal dominant nocturnal frontal lobe epilepsy
DOID:0060684 autosomal dominant nocturnal frontal lobe epilepsy 3
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025