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Protein patched

Summary

UniProt ID

P18502

Gene Symbol

CG2411
ptc

Gene ID

35851

Organism

Drosophila melanogaster (fruit fly)

External Links

PubChem: P18502
Re-Glyco: P18502

Annotation

Keyword

Glycoprotein
Receptor
Reference proteome
Segmentation polarity protein
Transmembrane helix

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
plasma membrane
cilium
basal plasma membrane
endocytic vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 16 in total

1

2

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GO Term
regulation of mitotic cell cycle
regulation of apoptotic process
segment polarity determination
axon guidance
eye-antennal disc morphogenesis
imaginal disc-derived wing morphogenesis
follicle cell of egg chamber development
wing disc anterior/posterior pattern formation
Bolwig's organ morphogenesis
determination of genital disc primordium

Displaying **all 6** entries
GO Term
smoothened binding
hedgehog receptor activity
phosphatidylinositol-4-phosphate binding
phosphatidic acid binding
hedgehog family protein binding
lipoprotein particle receptor activity

Annotation information from UniProt.

Sequence

MDRDSLPRVPDTHGDVVDEKLFSDLYIRTSWVDAQVALDQIDKGKARGSRTAIYLRSVFQSHLETLGSSVQKHAGKVLFVAILVLSTFCVGLKSAQIHSKVHQLWIQEGGRLEAELAYTQKTIGEDESATHQLLIQTTHDPNASVLHPQALLAHLEVLVKATAVKVHLYDTEWGLRDMCNMPSTPSFEGIYYIEQILRHLIPCSIITPLDCFWEGSQLLGPESAVVIPGLNQRLLWTTLNPASVMQYMKQKMSEEKISFDFETVEQYMKRAAIGSGYMEKPCLNPLNPNCPDTAPNKNSTQPPDVGAILSGGCYGYAAKHMHWPEELIVGGAKRNRSGHLRKAQALQSVVQLMTEKEMYDQWQDNYKVHHLGWTQEKAAEVLNAWQRNFSREVEQLLRKQSRIATNYDIYVFSSAALDDILAKFSHPSALSIVIGVAVTVLYAFCTLLRWRDPVRGQSSVGVAGVLLMCFSTAAGLGLSALLGIVFNAASTQVVPFLALGLGVDHIFMLTAAYAESNRREQTKLILKKVGPSILFSACSTAGSFFAAAFIPVPALKVFCLQAAIVMCSNLAAALLVFPAMISLDLRRRTAGRADIFCCCFPVWKEQPKVAPPVLPLNNNNGRGARHPKSCNNNRVPLPAQNPLLEQRADIPGSSHSLASFSLATFAFQHYTPFLMRSWVKFLTVMGFLAALISSLYASTRLQDGLDIIDLVPKDSNEHKFLDAQTRLFGFYSMYAVTQGNFEYPTQQQLLRDYHDSFVRVPHVIKNDNGGLPDFWLLLFSEWLGNLQKIFDEEYRDGRLTKECWFPNASSDAILAYKLIVQTGHVDNPVDKELVLTNRLVNSDGIINQRAFYNYLSAWATNDVFAYGASQGKLYPEPRQYFHQPNEYDLKIPKSLPLVYAQMPFYLHGLTDTSQIKTLIGHIRDLSVKYEGFGLPNYPSGIPFIFWEQYMTLRSSLAMILACVLLAALVLVSLLLLSVWAAVLVILSVLASLAQIFGAMTLLGIKLSAIPAVILILSVGMMLCFNVLISLGFMTSVGNRQRRVQLSMQMSLGPLVHGMLTSGVAVFMLSTSPFEFVIRHFCWLLLVVLCVGACNSLLVFPILLSMVGPEAELVPLEHPDRISTPSPLPVRSSKRSGKSYVVQGSRSSRGSCQKSHHHHHKDLNDPSLTTITEEPQSWKSSNSSIQMPNDWTYQPREQRPASYAAPPPAYHKAAAQQHHQHQGPPTTPPPPFPTAYPPELQSIVVQPEVTVETTHSDSNTTKVTATANIKVELAMPGRAVRSYNFTS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
142	N-linked (GlcNAc...) asparagine	UniProt
298	N-linked (GlcNAc...) asparagine	UniProt
335	N-linked (GlcNAc...) asparagine	UniProt
388	N-linked (GlcNAc...) asparagine	UniProt
807	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Assembly of the 'signalling complexes'	Drosophila melanogaster
Hedgehog 'off' state	Drosophila melanogaster
Hedgehog 'on' state	Drosophila melanogaster
Ligand-receptor interactions	Drosophila melanogaster

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:1289	neurodegenerative disease	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements